Association of Preferences for Papillary Thyroid Cancer Treatment With Disease Terminology: A Discrete Choice Experiment

JAMA Otolaryngology-- Head & Neck Surgery
Brooke NickelKirsten McCaffery

Abstract

Given recent evidence of overdiagnosis and overtreatment of small papillary thyroid cancers (PTCs) and other low-risk cancers, strategies are needed to help patients consider less invasive treatment options. To determine which factors influence treatment preferences for patients with PTC, and the trade-offs in treatment factors people are willing to accept, and to understand how terminology influences preferences and benefit-harm trade-offs. Preferences in PTC treatment were evaluated using a discrete choice experiment (DCE) conducted as a web-based survey using an existing public online research panel. Participants were randomized to receive 1 of 2 frames of information based on the terminology used to describe the condition: "cancer" or "lesion." Participants chose between 3 treatment options for PTC (thyroidectomy, hemithyroidectomy, and active surveillance). Analyses were conducted using a mixed logit model. The main outcome variable was treatment preference; attributes of treatment options and sociodemographic characteristics were explanatory variables. The DCE was completed by 2054 participants (993 [48.3%] men and 1061 [51.7%] women; mean [SD] age, 46.0 [16.5] years) with no history of thyroid cancer. Participants prefer...Continue Reading

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Citations

Jul 24, 2020·JAMA Otolaryngology-- Head & Neck Surgery·David FornerDavid Goldstein
Jan 23, 2020·Thyroid : Official Journal of the American Thyroid Association·Camilo Gonzalez-VelazquezMark L Urken
Mar 8, 2020·Thyroid : Official Journal of the American Thyroid Association·Sara AhmadiJulie Ann Sosa
Oct 31, 2020·Frontiers in Endocrinology·Jolanta KrajewskaDaria Handkiewicz-Junak
May 6, 2021·The Patient·Hannah CollacottSebastian Heidenreich
Aug 13, 2021·Journal of Cancer Survivorship : Research and Practice·G CreffI Licaj
Sep 2, 2021·Current Opinion in Endocrinology, Diabetes, and Obesity·Catherine B Jensen, Susan C Pitt

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