Association of radiographic and symptomatic knee osteoarthritis with health-related quality of life in a population-based cohort study in Japan: the ROAD study

Osteoarthritis and Cartilage
S MurakiN Yoshimura

Abstract

Knee osteoarthritis (OA) is a major public health issue causing chronic pain and disability. However, there is little information on the impact of this disease on quality of life (QOL) in Japanese men and women. The objective of the present study was to clarify the impact of radiographic and symptomatic knee OA on QOL in Japan. This study examined the association of radiographic and symptomatic knee OA with QOL parameters such as the Medical Outcomes Study Short Form-8 (SF-8), EuroQOL (EQ-5D) and Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC). Radiographic knee OA was defined according to Kellgren/Lawrence (KL) grades, and symptomatic knee OA was defined as KL=3 or 4 with knee pain. We also examined the independent association of symptomatic knee OA and grip strength with QOL. From the 3040 participants in the Research on Osteoarthritis Against Disability (ROAD) study, the present study analyzed 2126 subjects older than 40 years who completed the questionnaires (767 men and 1359 women; mean age, 68.9+/-10.9 years). Subjects with KL=3 or 4 had significantly lower physical QOL as measured by the physical component summary (PCS) score of the SF-8 and pain domains of the WOMAC, whereas mental QOL, as measure...Continue Reading

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Citations

Oct 7, 2011·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Noriko YoshimuraKozo Nakamura
Dec 21, 2011·Lab Animal·Boaz ArziKyriacos A Athanasiou
Mar 4, 2014·Die Naturwissenschaften·C HollandH S Gill
Jul 16, 2014·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Yoichi IizukaKenji Takagishi
Feb 11, 2014·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Toru AkuneNoriko Yoshimura
Sep 9, 2015·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Yoichi IizukaKenji Takagishi
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Mar 12, 2015·PM & R : the Journal of Injury, Function, and Rehabilitation·Won KimKyoung Hyo Choi
Feb 3, 2015·Osteoarthritis and Cartilage·S MurakiN Yoshimura
Jun 6, 2016·Journal of Orthopaedic Science : Official Journal of the Japanese Orthopaedic Association·Takashi OhsawaKenji Takagishi
Jul 5, 2016·Clinical Reviews in Bone and Mineral Metabolism·Noriko Yoshimura, Kozo Nakamura
Oct 18, 2015·BMC Musculoskeletal Disorders·Shigeyuki MurakiNoriko Yoshimura
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