PMID: 8447704Feb 1, 1993Paper

Association of radiographic changes of osteoarthritis, symptoms, and synovial fluid particles in 300 knees

Annals of the Rheumatic Diseases
M PattrickM Doherty

Abstract

Associations between compartmental distribution of radiographic changes of osteoarthritis (OA), individual features of OA (joint space loss, sclerosis, cyst, osteophyte; each scored 0-3), and presence of synovial fluid calcium particles (calcium pyrophosphate dihydrate (CPPD) crystals identified by polarised light microscopy and other calcium particles by alizarin red positivity (ARP) were sought in 300 osteoarthritic knees (178 patients; mean age 72, range 33-96 years). Patients whose knees were symptom free as well as those with symptoms were included. Osteoarthritis of two or three compartments but not unicompartmental OA was associated with the presence of CPPD or ARP. Involvement of any compartment (not just patellofemoral), and higher mean scores for both total and individual osteoarthritis changes (except cysts) was associated with CPPD and ARP; CPPD, but not ARP, was associated with symptoms: knees reported as having symptoms had higher mean total OA scores. Femoral cortical erosion, found more often in women, was associated with higher mean total OA score at the patellofemoral compartment but not with the presence of particles. Attrition, remodelling, and chondrocalcinosis (each scored as present or absent) occurred mo...Continue Reading

References

Dec 1, 1975·The Journal of Clinical Investigation·R M BennettD J McCarty
Feb 7, 1976·Lancet·P A DieppeD A Willoughby
Apr 1, 1979·Arthritis and Rheumatism·P B Halverson, D J McCarty
Jan 21, 1978·British Medical Journal·P A DieppeP R Crocker
May 1, 1979·Seminars in Arthritis and Rheumatism·J G Peyron
Aug 1, 1979·Annals of the Rheumatic Diseases·B B SeedholmV Wright
May 1, 1989·Seminars in Arthritis and Rheumatism·J L Merritt
May 1, 1989·Seminars in Arthritis and Rheumatism·T G Kantor
May 1, 1985·Arthritis and Rheumatism·P A GibiliscoK A Soper
Sep 1, 1988·Somatic Cell and Molecular Genetics·M G WatheletC Szpirer
Oct 1, 1985·Annals of the Rheumatic Diseases·A J Crisp
Feb 1, 1969·The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society·H PuchtlerM S Terry
Aug 1, 1983·Annals of the Rheumatic Diseases·J Chayen
Jan 1, 1983·Archives of Orthopaedic and Trauma Surgery·J IsolauriP Rokkanen

❮ Previous
Next ❯

Citations

Jul 26, 2011·Rheumatology International·Oliver NiggemeyerWolfgang Rüther
Sep 18, 2010·Archives of Orthopaedic and Trauma Surgery·Oliver NiggemeyerWolfgang Rüther
Jun 7, 2008·Chemical Communications : Chem Comm·Aaron Hernandez-SantanaGillian P McMahon
Jul 1, 1994·Annals of the Rheumatic Diseases·A SwanP Dieppe
Jan 1, 1995·Annals of the Rheumatic Diseases·J LedinghamM Doherty
May 26, 2009·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·Mansur AhmadEric L Schiffman
Apr 29, 2010·Current Rheumatology Reports·Johannes NowatzkySvetlana Krasnokutsky
Apr 8, 2014·Rheumatic Diseases Clinics of North America·Abhishek Abhishek, Michael Doherty
Jan 15, 2013·Rheumatic Diseases Clinics of North America·A Abhishek, Michael Doherty
Jul 27, 2001·Osteoarthritis and Cartilage·T A Hammad
Nov 5, 2014·Dento Maxillo Facial Radiology·T A LarheimL Z Arvidsson
Dec 13, 2016·Current Opinion in Rheumatology·Alyssa K CarlsonRonald K June
May 15, 1997·Microscopy Research and Technique·D L GardnerK Oates
May 1, 1995·Veterinary Surgery : VS·A M Rørvik, A M Grøndahl
Dec 14, 2011·Clinical Orthopaedics and Related Research·Philippe HernigouAlexandre Poignard

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.