Association of renal function, estimated by four equations, with coronary artery disease

International Urology and Nephrology
Yusuf C DoganerKenan Saglam

Abstract

Individuals with impaired renal function are at increased risk of coronary artery disease (CAD). CAD is also associated with an increased likelihood of having chronic kidney disease (CKD). In the present study, we sought to determine the association between impaired renal function with CAD presence and CAD severity based on four different estimated glomerular filtration rate (eGFR) equations. We estimated GFR values using four equations: modification of diet in renal disease (MDRD), Cockcroft-Gault (C-G), chronic kidney disease epidemiology (CKD-Epi), and Mayo Quadratic. Three hundred and fifty-six CAD patients were classified by the number of stenotic coronary arteries occluded >50%, while the CAD severity was categorized based on the number of involved coronary arteries determined to be healthy, single- and multi-vessel disease. The mean values of eGFR calculated by CKD-Epi, MDRD, Mayo, and C-G equations were 77.44, 71.34, 96.33, and 89.49 mL/min/1.73 m(2) respectively. Based on these equations, the prevalence of eGFR <60 mL/min/1.73 m(2) among the patients with significant CAD was 41.5, 45.2, 50, and 42.9%, respectively. eGFR values calculated by four formulas were significantly higher in healthy subjects than those with sin...Continue Reading

References

Jan 1, 1976·Nephron·D W Cockcroft, M H Gault
Aug 21, 2002·Circulation·Jassim Al SuwaidiUNKNOWN PARAGON-A Investigators. Platelet IIb/IIIa Antagonism for the Reduction of Acute coronary syndrome events in a Global Organi
Oct 19, 2002·Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association·Francesco LocatelliPietro Pozzoni
Mar 19, 2003·Seminars in Dialysis·Katrin UhligMark J Sarnak
Mar 19, 2003·Seminars in Dialysis·François Madore
Jul 16, 2003·Annals of Internal Medicine·Andrew S LeveyUNKNOWN National Kidney Foundation
Dec 24, 2004·European Heart Journal·Lennart G BongartzBranko Braam
Aug 26, 2006·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·Daniel E WeinerMark J Sarnak
Nov 30, 2007·American Journal of Nephrology·Michel ChoncholNancy R Kressin
May 6, 2009·Annals of Internal Medicine·Andrew S LeveyUNKNOWN CKD-EPI (Chronic Kidney Disease Epidemiology Collaboration)
Nov 27, 2009·Angiology·Kadriye Orta KilickesmezTevfik Gurmen

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