Abstract
Data on new-onset seizures after treatment of aneurysmal subarachnoid hemorrhage (aSAH) patients are limited and variable. We examined the association between new-onset seizures after aSAH and aneurysm treatment modality, as well their relationship with initial clinical severity of aSAH and outcomes. This is a retrospective cohort study of all aSAH patients admitted to our institution over a 6-year period. 'Seizures' were defined as any observed clinical seizure or electrographic seizure on continuous electroencephalogram (cEEG) recordings, as determined by the reviewing neurophysiologist. Subgroup analyses were performed in low-grade (Hunt-Hess 1-3) and high-grade (Hunt-Hess 4-5) patients. Outcomes measures were Glasgow Coma Score (GCS) at intensive care unit (ICU) discharge and modified Rankin Scale (mRS) at outpatient follow-up. There were 282 patients with aSAH; 203 (72.0%) suffered low-grade and 79 (28%) high-grade aSAH. Patients were treated with endovascular coiling (N = 194, 68.8%) or surgical clipping (N = 66, 23.4%). Eighteen (6.4%) patients had seizures, of whom 10 (5.5%) had aneurysm coiling and 7 (10.6%) underwent clipping (p = 0.15). In low-grade patients, seizures occurred less frequently (p = 0.016) and were mor...Continue Reading
References
Jan 1, 1990·Acta neurochirurgica·S FranceschettiG Avanzini
May 1, 1983·Journal of Neurosurgery·J B NorthW B Taylor
Jan 1, 1995·British Journal of Neurosurgery·B O HütterI Kreitschmann
Jun 9, 2000·Journal of Clinical Neuroscience : Official Journal of the Neurosurgical Society of Australasia·M L ThorpeG K Herkes
Sep 22, 2000·Epilepsia·E OlafssonW A Hauser
Mar 21, 2002·Epilepsia·Antonio De SantisEmilio Perucca
Oct 18, 2002·Neurosurgery·Lyle J DennisStephan A Mayer
Jan 29, 2003·Neurology·J ClaassenS A Mayer
Feb 20, 2003·Neurosurgery·James V ByrneZoe Traill
Sep 6, 2005·Lancet·Andrew J MolyneuxUNKNOWN International Subarachnoid Aneurysm Trial (ISAT) Collaborative Group
Apr 22, 2006·Neurocritical Care·Jan ClaassenStephan A Mayer
Jun 5, 2007·Journal of Neurosurgery·Andrew S LittleRobert F Spetzler
Apr 19, 2011·Neurosurgery·Brian L HohFred G Barker
Jul 21, 2011·Neurocritical Care·Michael N DiringerUNKNOWN Neurocritical Care Society
Sep 29, 2011·Journal of Neurology·Sanne M Dorhout MeesAndrew J Molyneux
May 5, 2012·Stroke; a Journal of Cerebral Circulation·E Sander ConnollyUNKNOWN Council on Clinical Cardiology
Apr 26, 2013·Neurosurgery·Fred RinconAaron Dumont
Jul 3, 2013·Annals of Neurology·Jan ClaassenGeorge Hripcsak
Jul 25, 2013·British Journal of Neurosurgery·Christine BrandThomas Kapapa
Oct 23, 2013·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Mary Ziemba-DavisAaron A Cohen-Gadol
Aug 15, 2014·Journal of Neurology·Maria WostrackYu-Mi Ryang
May 8, 2015·Neurology·Jukka HuttunenArto Immonen
Aug 5, 2016·Seizure : the Journal of the British Epilepsy Association·Barret RushPaul Hertz
Oct 17, 2016·World Neurosurgery·Sami RidwanAzize Boström
Citations
May 28, 2019·Current Neurology and Neuroscience Reports·Joseph W Doria, Peter B Forgacs
Mar 12, 2019·Current Opinion in Critical Care·Baxter Allen, Paul M Vespa
Oct 23, 2020·Acta Neurologica Scandinavica·Sonja Holm-YildizDaniel Kondziella
Dec 4, 2020·Clinical Neurology and Neurosurgery·Yoshichika KikutaTakakazu Kawamata
Mar 5, 2021·Journal of Epilepsy Research·Ezequiel García-BallestasLuis-Rafael Moscote-Salazar