Association of Self-Rated Health in Midlife With Mortality and Old Age Frailty: A 26-Year Follow-Up of Initially Healthy Men

The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences
Emmi HuohvanainenTimo E Strandberg

Abstract

The aim was to investigate the relationship between self-rated health (SRH) in healthy midlife, mortality, and frailty in old age. In 1974, male volunteers for a primary prevention trial in the Helsinki Businessmen Study (mean age 47 years, n = 1,753) reported SRH using a five-step scale (1 = "very good," n = 124; 2 = "fairly good," n = 862; 3 = "average," n = 706; 4 = "fairly poor," or 5 = "very poor"; in the analyses, 4 and 5 were combined as "poor", n = 61). In 2000 (mean age 73 years), the survivors were assessed using a questionnaire including the RAND-36/SF-36 health-related quality of life instrument. Simplified self-reported criteria were used to define phenotypic prefrailty and frailty. Mortality was retrieved from national registers. During the 26-year follow-up, 410 men had died. Frailty status was assessed in 81.0% (n = 1,088) of survivors: 434 (39.9%), 552 (50.7%), and 102 (9.4%) were classified as not frail, prefrail, and frail, respectively. With fairly good SRH as reference, and adjusted for cardiovascular risk in midlife and comorbidity in old age, midlife SRH was related to mortality in a J-shaped fashion: significant increase with both very good and poor SRH. In similar analyses, average SRH in midlife (n = 4...Continue Reading

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Citations

Jul 22, 2016·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Bu B YeapLeon Flicker
Mar 31, 2017·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·John W LiangMandip S Dhamoon
Feb 9, 2018·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Annele UrtamoTimo E Strandberg
Apr 17, 2018·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Timo E StrandbergHannu Kautiainen
Apr 20, 2019·Workplace Health & Safety·Ashley Helvig CoombeEileen R Chasens
Aug 25, 2019·Journal of the American Geriatrics Society·Mikaela B von BonsdorffTimo E Strandberg
Dec 25, 2019·BMC Geriatrics·Hanna Falk ErhagAnnika Bergström
Oct 24, 2019·The Journal of Nutrition, Health & Aging·E DentB Vellas
Oct 3, 2018·Journal of Aging and Health·Lynn M BaniakEileen R Chasens
Dec 26, 2018·Aging Clinical and Experimental Research·Annele UrtamoTimo E Strandberg
Oct 4, 2021·Health and Quality of Life Outcomes·Ellen LindellCaterina Finizia
Nov 19, 2021·The Journals of Gerontology. Series B, Psychological Sciences and Social Sciences·Katie M JajtnerSophie Mitra

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