Association of Serum Level of 25-Hydroxy Vitamin D Deficiency and Pulmonary Function in Healthy Individuals

TheScientificWorldJournal
Maryam MoghaddassiZahra Alipour

Abstract

Besides the extensive regulatory role in growing number of biologic processes, vitamin D has been recently considered essential for lungs function as well as protective against exacerbation of chronic obstructive pulmonary diseases. We assessed the correlation between vitamin D serum levels with pulmonary function in healthy individuals. In a cross-sectional study, healthy volunteer (n = 92) participants underwent the following laboratory procedures: a blood test, a 24-hour urine collection test, and the serum level of 25-hydroxy vitamin D before undergoing spirometry. Linear correlation coefficient was calculated to detect the association between serum level of 25-hydroxy vitamin D and pulmonary volumes. The mean age of participants was 39.95 ± 9.98 years. 48% of participants showed different levels of 25-hydroxy vitamin D deficiency. We recognized a consistent direct positive correlation between serum levels of 25-hydroxy vitamin D and lung function volumes. The coefficient for forced vital capacity, forced expiratory volume in 1 second, forced expiratory flow 25-75%, and forced expiratory volume in 1 second/forced vital capacity ratio were 0.610, 0.509, 0.454, and 0.551, respectively. Our findings suggest correlation between...Continue Reading

References

Aug 2, 2003·Schizophrenia Research·John McGrathStephen Buka
Jan 20, 2004·Arthritis and Rheumatism·Linda A MerlinoUNKNOWN Iowa Women's Health Study
Aug 24, 2004·The Journal of Immunology : Official Journal of the American Association of Immunologists·Tian-Tian WangJohn H Hanrahan
Dec 9, 2004·The American Journal of Clinical Nutrition·Daniel J Raiten, Mary Frances Picciano
Jan 27, 2005·The Journal of Nutrition·Mona S CalvoCurtis N Barton
Jun 30, 2005·FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology·Adrian F GombartH Phillip Koeffler
Jul 19, 2005·The Journal of Steroid Biochemistry and Molecular Biology·Jacqueline MorenoDavid Feldman
Sep 22, 2005·Archives of Disease in Childhood·G DasM Z Mughal
Oct 28, 2005·The Journal of Nutrition·Michael F Holick
Dec 21, 2006·JAMA : the Journal of the American Medical Association·Kassandra L MungerAlberto Ascherio
Sep 8, 2007·The American Journal of Clinical Nutrition·Ilkka LaaksiTimo Ylikomi
Jun 23, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A MithalUNKNOWN IOF Committee of Scientific Advisors (CSA) Nutrition Working Group
Jan 16, 2010·American Journal of Respiratory and Critical Care Medicine·E Rand SutherlandDonald Y M Leung
Dec 3, 2010·Respiration; International Review of Thoracic Diseases·Fei LiXiang Gao
Jun 10, 2011·Thorax·Seif O ShaheenElaine M Dennison
Sep 6, 2012·Proceedings of the National Academy of Sciences of the United States of America·Anna K CoussensAdrian R Martineau
Nov 19, 2013·The Journal of Steroid Biochemistry and Molecular Biology·Cristina Palacios, Lilliana Gonzalez
Jan 28, 2014·The Lancet. Respiratory Medicine·Wim JanssensHannelie Korf
Oct 6, 2014·The Journal of Pediatrics·Tsung-Chieh YaoUNKNOWN Prediction of Allergies in Taiwanese Children (PATCH) Study Group
Jun 6, 2015·PloS One·Evgeni MekovMaya Tafradjiiska
Mar 24, 2016·BMC Psychiatry·J LallyF Gaughran

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Methods Mentioned

BETA
urine collection
enzyme-linked immunosorbent assay

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