Association of serum uric acid levels with SYNTAX score II and long term mortality in the patients with stable angina pectoris who undergo percutaneous coronary interventions due to multivessel and/or unprotected left main disease

The International Journal of Cardiovascular Imaging
Yavuz KarabağHalil Ibrahim Tanboğa

Abstract

Serum uric acid (SUA) level was shown in various studies to be related to the presence of coronary artery disease and subsequent cardiovascular events. The aim of the present study was to evaluate the association of SUA with SYNTAX score II (SSII) and the long-term prognosis of patients with stable angina pectoris who underwent percutaneous revascularization due to multivessel disease (MVD) and/or unprotected left main disease (UPLMD). Two-hundred and ninety patients with MVD and/or UPLMD who were treated consecutively with percutaneous coronary intervention (PCI) were included in the present study. The study population was divided into high SSII (n: 145; SSII > 32.9) and low SSII (n: 145; SSII ≤ 32.9) according to the median SSII value. The SUA value was significantly higher in the high SSII group than in the low SSII group (5.53 ± 1.95 vs. 6.07 ± 1.88; p = 0.001) and was found to be an independent predictor of high SSII (OR 1.306; 95% CI 1.119-1.525; p = 0,001). Twenty-eight patients (9.7%) died during the long-term follow-up, and SUA and SSII were additionally found to be independent predictors of long-term mortality (HR 1.245, 95% CI 1.046-1.482, p = 0.014; HR 1.042, 95% CI 1.007-1.079, p = 0.018, respectively). In the pres...Continue Reading

References

Feb 1, 1983·The American Journal of Cardiology·G G Gensini
Dec 17, 1997·The American Journal of Cardiology·J N HamburgerY Taeymans
Mar 6, 2002·Circulation·Peter LibbyAttilio Maseri
Feb 7, 2003·Journal of the American College of Cardiology·Katsuomi IwakuraKenshi Fujii
Mar 31, 2005·American Journal of Hypertension·Richard J JohnsonJaime Herrera-Acosta
May 6, 2006·Stroke; a Journal of Cerebral Circulation·Michiel J BosMonique M B Breteler
May 24, 2006·Atherosclerosis·Nobukazu IshizakaMinoru Yamakado
Sep 18, 2007·Journal of the American College of Cardiology·James K MinTracy Q Callister
Jun 28, 2008·International Journal of Cardiology·William J van GaalAdrian P Banning
Aug 10, 2013·Heart and Vessels·Tokiko MiyaokaKosaku Nitta
Feb 18, 2014·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Pascal VranckxStephan Windecker
Jul 8, 2014·Circulation Journal : Official Journal of the Japanese Circulation Society·Carlos M CamposPatrick W Serruys
Feb 28, 2015·Scandinavian Journal of Clinical and Laboratory Investigation·Yu ZhuYu-Feng Wen
Sep 4, 2015·Lancet·Raffaele PiccoloStephan Windecker
Sep 29, 2015·Current Medical Research and Opinion·Richard J Johnson
Mar 31, 2016·Clinical and Experimental Hypertension : CHE·Bei WangChang Zhao
Feb 17, 2017·Journal of Atherosclerosis and Thrombosis·Yoko SotodaIchiro Wakabayashi
Sep 11, 2017·The International Journal of Cardiovascular Imaging·Mert İlker HayıroğluSeçkin Pehlivanoğlu

❮ Previous
Next ❯

Citations

Apr 22, 2020·The International Journal of Cardiovascular Imaging·Mehmet MustuZafer Buyukterzi
Apr 14, 2020·The International Journal of Cardiovascular Imaging·Johan H C ReiberJoachim Lotz
Apr 4, 2021·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Alessandro MalobertiCristina Giannattasio

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.