Association of symptoms of type 2 diabetic patients with severity of disease, obesity, and blood pressure

Diabetes Care
C J BulpittA E Fletcher

Abstract

The symptoms of 430 type 2 diabetic patients were determined by a self-administered questionnaire before entry into the U.K. Prospective Diabetes Study. Entry into the trial followed 2 months of dietary treatment for newly diagnosed patients with type 2 diabetes. Forty symptoms with five levels of severity were included in the questionnaire. A complaint rate was computed as the sum of symptom scores divided by the number of symptom questions answered. The complaint rate was independently and positively related to BMI, fasting plasma glucose (FPG), and being a woman. Three symptoms--presence of dry mouth (P < 0.001), thirst (P < 0.01), and stomach pain (P = 0.02)--were related to FPG independent of sex, age, BMI, or blood pressure. Only dry mouth was related to HbA1c (P = 0.05). Complaints of shortness of breath, swollen ankles, headaches, heartburn, sweating, wheezing, nocturia, thirst, and diarrhea increased with BMI independently of other variables. A complaint of cold extremities decreased with BMI. Heartburn, weakness of limbs, and hot flushes were positively related to blood pressure, and unsteadiness was negatively related. The symptoms reported by patients with type 2 diabetes increased with FPG and markedly with BMI. Th...Continue Reading

Citations

Aug 5, 2000·Maturitas·R Asplund, H E Aberg
May 26, 1999·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·J H SummersonJ C Konen
Apr 28, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·I J van den ArendG J Schrijvers
Nov 10, 2000·Diabetic Medicine : a Journal of the British Diabetic Association·M NelsonK Start
Aug 16, 2000·Thorax·G J Gibson
Jan 10, 2008·Western Journal of Nursing Research·Holli A DeVonKaren Larimer
Jul 27, 2007·Current Medical Research and Opinion·Louis S MatzaJodi M Shorr
Jul 16, 2010·Journal of Psychosomatic Research·Cynthia Fritschi, Laurie Quinn
Mar 22, 2005·Research in Nursing & Health·Holli A DeVonJulie Johnson Zerwic
Aug 13, 2004·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·N J TalleyM Horowitz
May 20, 2003·Journal of Advanced Nursing·Colin J GreavesJ W Stead
Dec 23, 2009·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·N ManabeA R Zinsmeister
Jun 29, 2011·Scandinavian Journal of Primary Health Care·Anni B S NielsenNiels de Fine Olivarius
Aug 4, 2007·Health and Quality of Life Outcomes·Louis S MatzaNicole Yurgin
Nov 9, 2016·PloS One·Rupali SinghPatricia Kluding
Apr 7, 2006·American Journal of Epidemiology·Kari A O TikkinenTeuvo L J Tammela
Jun 21, 2012·The Diabetes Educator·Cynthia FritschiCarol E Ferrans
Nov 8, 2018·BMC Endocrine Disorders·Anjali GopalanMarilyn M Schapira
Jan 23, 2018·International Journal of Colorectal Disease·Noriaki ManabeKen Haruma
Jun 9, 2021·Experimental and Clinical Endocrinology & Diabetes : Official Journal, German Society of Endocrinology [and] German Diabetes Association·Nicolle MüllerChristof Kloos

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