Association of three SNPs in adiponectin gene with lipid traits of Tianzhu Black Muscovy (Cairina moschata).

Molecular Biology Reports
Yuan-Yu QinLei Wu

Abstract

Adiponectin plays a critically biological role in atherosclerosis, glucose utilization, lipid and carbohydrate metabolism, and triglyceride synthesis in animals and humans. However, little is known about the effect of adiponectin on lipid metabolism of the avian species. The aim of the preset study was to investigate the potential associations between adiponectin gene single nucleotide polymorphisms (SNPs) and the lipid traits in 348 females of Tianzhu Black Muscovy. Three novel SNPs (167G>A, 290T>C and 711G>A) were detected in adiponectin gene. 167G>A and 290T>C has linked very closely, and then 711G>A with 167G>A and 290T>C has no strong linkage disequilibrium, respectively. The Chi square test showed that allelic frequency and genotype frequency of two SNPs (167G>A and 711G>A) didn't agree with the Hardy-Weinberg equilibrium (P>0.05). Four haplotypes and nine diplotypes were formed on the three SNPs of adiponectin gene. Association analysis indicated that the 167G>A genotypes were strongly associated with intramuscular fat (IMF) of chest muscle and serum total cholesterol (TC) (P < 0.01); the 290T>C genotypes were strongly associated with IMF, TC, and serum triglyceride (TG) (P < 0.01); furthermore, the 711G>A genotypes were...Continue Reading

References

Apr 23, 2002·Nature Reviews. Genetics·Kristin G ArdlieMark Seielstad
May 16, 2006·Domestic Animal Endocrinology·Ramesh RamachandranShana L Metzger
Aug 8, 2007·Yi chuan = Hereditas·Biao DongZhi-Liang Gu
Jul 29, 2008·Reproduction : the Official Journal of the Society for the Study of Fertility·Olga M Ocón-GroveRamesh Ramachandran
Mar 17, 2010·BioFactors·Yiyi Sun, Xiuping Chen
Mar 28, 2012·Hormones : International Journal of Endocrinology and Metabolism·Adeeb ShehzadYoung Sup Lee
Sep 29, 2012·Vitamins and Hormones·Marie-France PalinBruce D Murphy
May 28, 2013·General and Comparative Endocrinology·Ramesh RamachandranJill A Hadley
Jul 23, 2013·Journal of Molecular Biology·Shannon SteflEmil Alexov
Jul 31, 2013·Journal of Animal Physiology and Animal Nutrition·J YanC Sun
Jan 30, 2014·Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire·Yan JunSun Chao
Oct 16, 2014·American Journal of Physiology. Endocrinology and Metabolism·Marta KiezunTadeusz Kaminski
Jul 27, 2015·Molecular Biology Reports·Moshen JafarikiaMarie-France Palin
Aug 1, 2015·Reproductive Biology and Endocrinology : RB&E·Mélodie DiotJoëlle Dupont
Mar 20, 2016·Journal of Molecular Cell Biology·Zhao V Wang, Philipp E Scherer
Jun 22, 2017·International Journal of Molecular Sciences·Arunkumar E Achari, Sushil K Jain
Jul 12, 2017·Critical Reviews in Oncology/hematology·Santoshi MuppalaGanji Purnachandra Nagaraju
Jun 2, 2018·International Journal of Endocrinology·Kamil DobrzynTadeusz Kaminski
Jun 29, 2018·General and Comparative Endocrinology·Namya MelloukJoëlle Dupont
Jul 19, 2018·International Journal of Endocrinology·Namya MelloukJoëlle Dupont
Sep 15, 2018·Therapeutics and Clinical Risk Management·Izabela RozmilowskaMonika Adamczyk-Sowa
Sep 17, 2018·The American Journal of the Medical Sciences·Marziyeh YousefianEskandar Kamali-Sarvestani
Sep 20, 2018·Endocrinology and Metabolism·Ji Sun NamChul Woo Ahn

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Datasets Mentioned

BETA
GQ873067

Methods Mentioned

BETA
PCR

Software Mentioned

Primer
SHEsis
AlignIR
SPSS

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