Association of thromboelastography profile with severity of liver cirrhosis and portal venous system thrombosis.

BMC Gastroenterology
Yanglan HeXingshun Qi

Abstract

Hemostasis profile is often complicated in liver cirrhosis. Thromboelastography is a global viscoelastic test recommended by the current practice guideline and consensus. This cross-sectional study aimed to evaluate the association of thromboelastography profile with severity of liver cirrhosis and presence of portal venous system thrombosis (PVST). Overall, 116 and 50 cirrhotic patients were included in the Shenyang and Xi'an cohorts, respectively. Thromboelastography parameters were compared between cirrhotic patients with Child-Pugh class A and B/C, those with and without decompensated events, and those with and without PVST. Hypercoagulability would be considered if at least two of the following thromboelastography parameters were met: shortened reactive time (R), shortened coagulation time (K), increased angle, and increased maximum amplitude (MA). In the Shenyang cohort, 16 patients had shortened R, of whom seven (43.75%) had prolonged K and 11 (68.75%) decreased MA. In the Xi'an cohort, 24 patients had shortened R, of whom seven (29.17%) had prolonged K and 15 (62.50%) decreased MA. In the Shenyang cohort, the prevalence of hypercoagulability was not significantly different between cirrhotic patients with Child-Pugh clas...Continue Reading

References

Dec 1, 1990·American Journal of Clinical Pathology·P A McVay, P T Toy
Apr 3, 2002·Seminars in Liver Disease·Lucio AmitranoAntonio Balzano
Feb 24, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Armando TripodiPier Mannuccio Mannucci
Sep 29, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Stephen H CaldwellUNKNOWN Coagulation in Liver Disease Group
Mar 3, 2009·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Håkon ReikvamTor Hervig
Jun 16, 2010·Journal of Hepatology·Ton LismanUNKNOWN Coagulation in Liver Disease Study Group
Nov 29, 2012·The American Journal of the Medical Sciences·Xingshun QiGuohong Han
May 17, 2014·World Journal of Gastroenterology : WJG·Salman NusratMohammad F Madhoun
Jun 27, 2014·Seminars in Thrombosis and Hemostasis·Gianfranco Cervellin, Giuseppe Lippi
Jun 17, 2015·World Journal of Gastroenterology : WJG·Damian J HardingDhiraj Tripathi
Jul 24, 2015·Current Opinion in Hematology·Armando Tripodi
Sep 2, 2015·Expert Review of Gastroenterology & Hepatology·Xingshun QiXiaozhong Guo
Dec 8, 2015·Hematology·Jody L Kujovich
Jan 23, 2017·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Alberto ZanettoPaolo Simioni
Feb 23, 2017·Annals of Laboratory Medicine·Kyung Hwa ShinMong Cho
Dec 14, 2017·Journal of Clinical and Experimental Hepatology·Vaibhav SomaniApurva Shah
Jun 30, 2018·Saudi Journal of Gastroenterology : Official Journal of the Saudi Gastroenterology Association·Jing LiXingshun Qi
Mar 28, 2019·Digestive Diseases and Sciences·Ruhail KohliKiran Bambha
Apr 16, 2019·Gastroenterology·Jacqueline G O'LearyStephen H Caldwell
Jul 30, 2019·European Journal of Gastroenterology & Hepatology·Xiaoquan HuangShiyao Chen
Aug 26, 2019·The Journal of Surgical Research·Betty ZhangPablo E Serrano

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