Association of tumor satellite distance with prognosis and contralateral neck recurrence of tongue squamous cell carcinoma

Head & Neck
Tsung-Lin YangPei-Jen Lou

Abstract

The margin status is an important prognosticator for the survival of patients with tongue cancer. Although a positive margin is associated with a poor prognosis, those with clear margins do not always have good clinical outcomes. We investigated the margin status, pattern of tumor invasion (POI), and tumor satellite distance (TSD) in 119 freshly treated tongue cancers and assessed their association with the characteristics and clinical outcomes. A close or clear margin and POI were not associated with overall survival. Tumor satellites occurred in 92% of tumors and were significantly associated with betel nut exposure. Patients with TSD <or=0.5 mm had significantly better overall survival. Patients with TSD >0.5 mm had a higher incidence of local recurrence, shorter intervals to neck recurrence, and a higher propensity to contralateral or bilateral cervical nodal metastasis. TSD is associated with local recurrence, contralateral neck metastasis, and the overall survival of patients with tongue cancer.

References

Sep 9, 1992·International Journal of Cancer. Journal International Du Cancer·K Sundqvist, R C Grafström
Oct 1, 1990·American Journal of Surgery·T R Loree, E W Strong
Sep 1, 1989·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·M BryneE Dabelsteen
Jun 1, 1987·International Journal of Radiation Oncology, Biology, Physics·T Y ChenD L Driscoll
Feb 16, 1995·The New England Journal of Medicine·J A BrennanD Sidransky
Apr 29, 1998·American Journal of Surgery·P W YuenL K Lam
May 26, 1999·Advances in Anatomic Pathology·J G Batsakis
Mar 7, 2003·American Journal of Surgery·Susumu ShingakiChikara Saito
May 7, 2004·The New England Journal of Medicine·Jay S CooperUNKNOWN Radiation Therapy Oncology Group 9501/Intergroup
Jun 3, 2004·Clinical Cancer Research : an Official Journal of the American Association for Cancer Research·Viola M M van HoutenRuud H Brakenhoff
Jan 13, 2005·The American Journal of Surgical Pathology·Margaret Brandwein-GenslerBeverly Yiyao Wang
Jun 11, 2005·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·H KurokawaT Takahashi

❮ Previous
Next ❯

Citations

Nov 25, 2014·Indian Journal of Surgical Oncology·Sivakumar VidhyadharanKrishnakumar Thankappan
Jun 15, 2011·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Tsung-Lin YangJenq-Yuh Ko
Dec 18, 2012·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·Gianlorenzo Dionigi
Aug 12, 2017·Current Oncology Reports·Dante De PazKai-Ping Chang
Apr 10, 2018·Virchows Archiv : an International Journal of Pathology·Y M PuQ G Hu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carcinoma, Squamous Cell

Basal cell carcinoma is a form of malignant skin cancer found on the head and neck regions and has low rates of metastasis. Discover the latest research on basal cell carcinoma here.

Related Papers

Risk Analysis : an Official Publication of the Society for Risk Analysis
J J McCormick, V M Maher
Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons
Deepak KademaniLouis Homer
© 2021 Meta ULC. All rights reserved