Association of Urinary Phytoestrogens With Pelvic Organ Prolapse and Fecal Incontinence Symptoms in Postmenopausal Women

Female Pelvic Medicine & Reconstructive Surgery
Olivia Orlinda Cardenas-TrowersAlayne D Markland

Abstract

The aim of this study was to investigate the association between urinary phytoestrogen levels with symptoms of pelvic organ prolapse (POP) and fecal incontinence (FI) in postmenopausal women. This is a cross-sectional study using the National Health and Nutrition Examination Survey database from 2005 to 2010 including postmenopausal women 40 years or older who either had both ovaries removed and/or had no period in the past year due to hysterectomy and/or menopause. Urinary concentrations of 6 phytoestrogens were measured. Pelvic organ prolapse symptoms were defined as a positive response to the question, "Do you see or feel a bulge in the vaginal area?" Fecal incontinence was defined as leakage of mucus, liquid, or solid stool occurring at least monthly. Using appropriate sample weights, prevalence estimates and 95% confidence intervals were calculated. Logistic regression was performed assessing associations between pelvic floor symptoms and log-transformed phytoestrogen levels adjusting for appropriate covariates. Participants included 1341 postmenopausal women with phytoestrogen data; 1213 with or without POP symptoms and 1221 with or without FI symptoms. Multivariable analysis revealed no association of urinary phytoestrog...Continue Reading

References

Feb 1, 1991·American Journal of Obstetrics and Gynecology·K HaademH Graffner
Dec 1, 1981·American Journal of Obstetrics and Gynecology·C S IosifB Astedt
Mar 1, 1997·British Journal of Obstetrics and Gynaecology·V DonnellyC O'Herlihy
May 13, 1998·European Journal of Obstetrics, Gynecology, and Reproductive Biology·G Oettling, H B Franz
Sep 15, 2001·Journal of General Internal Medicine·K KroenkeJ B Williams
Nov 13, 2001·Journal of Women's Health & Gender-based Medicine·P CopasM R Caudle
Jun 18, 2002·American Journal of Obstetrics and Gynecology·Susan L HendrixAnne McTiernan
Apr 16, 2004·Toxicological Sciences : an Official Journal of the Society of Toxicology·Stefan O MuellerKenneth S Korach
Aug 11, 2006·Nutrition and Cancer·Lilian U ThompsonNancy Kreiger
Sep 13, 2007·JAMA : the Journal of the American Medical Association·Carlos O WeissBruce Leff
Jul 19, 2008·Colorectal Disease : the Official Journal of the Association of Coloproctology of Great Britain and Ireland·G PinedoA Zúñiga
Sep 19, 2008·JAMA : the Journal of the American Medical Association·Ingrid NygaardUNKNOWN Pelvic Floor Disorders Network
Nov 26, 2009·Obstetrics and Gynecology·Jennifer M WuEvan R Myers
Jan 28, 2014·Obstetrics and Gynecology·Jennifer M WuAlayne D Markland
Nov 22, 2014·Obstetrics and Gynecology·David D RahnUNKNOWN Society of Gynecologic Surgeons Systematic Review Group
Jan 13, 2016·The American Journal of Gastroenterology·Alayne D MarklandRebecca G Rogers
Feb 13, 2018·Female Pelvic Medicine & Reconstructive Surgery·Olivia Cardenas-TrowersIlana Addis

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.