Association of visual field severity and parapapillary retinal blood flow in open-angle glaucoma

Journal of Glaucoma
Sunil DeokuleR N Weinreb

Abstract

To examine the association of the parapapillary blood flow parameters with severity of visual field loss (VFL) in open-angle glaucoma (OAG) patients. Observational clinical study. Fifty-two patients with OAG and 30 normal subjects were studied prospectively. Parapapillary blood flow parameters were obtained for superotemporal and inferotemporal quadrants using the scanning laser Doppler flowmeter. Mean deviation score was used to determine the severity of VFL both as continuous variable and stratified by severity: no VFL (OAG A) <or= 2 dB, mild VFL (OAG B) from 2.1 to 6 dB and moderate-severe VFL (OAG C) >6 dB. In the OAG patients with an abnormal Glaucoma Hemifield Test, the hemifield with a predominant VFL was determined. Linear regression analysis and analysis of covariance were used to assess the relationship between the severity of the VFL and the parapapillary blood flow parameters. The variance in mean parapapillary blood flow was assessed using standard deviation (SD) and coefficient of variation (COV). There was no correlation between the severity of VFL and parapapillary blood flow parameters. Variance in the mean parapapillary blood flow was significantly greater in OAG patients with VFL compared with OAG patients wi...Continue Reading

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Citations

May 24, 2013·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Jay ChhablaniWilliam R Freeman
Oct 27, 2010·Clinical & Experimental Ophthalmology·Masahide YanagiYoshiaki Kiuchi
Jan 28, 2014·Acta Ophthalmologica·Andrew HuckLeslie Abrams-Tobe
Sep 5, 2018·Acta Ophthalmologica·Robert KromerBernd Junker
Jul 27, 2010·Acta Ophthalmologica·Alon HarrisIngrida Januleviciene
Jun 16, 2012·Nature Reviews. Drug Discovery·Kang ZhangRobert N Weinreb
Apr 27, 2011·Acta Ophthalmologica·Yochai Z ShoshaniBarbara Wirostko
Jun 25, 2016·Current Eye Research·Natalia I KuryshevaAlexey V Fomin
Jan 19, 2012·Ophthalmic Surgery, Lasers & Imaging : the Official Journal of the International Society for Imaging in the Eye·Ranjith K KonduruSrinivas R Sadda

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