Association of vitamin D3 with alveolar bone regeneration in dogs

Journal of Cellular and Molecular Medicine
Hsiang-Hsi HongTing-An Chou

Abstract

Designed sockets prepared on the mandibles of nine Beagle dogs were divided into three groups: Calcitriol +Alloplast, Alloplast and Empty. Five of the nine dogs received Vit.D3 and calcium supplement (Vit.D/Ca group), while the other four dogs without supplements were assigned to Non-Vit.D/Ca group. After 4 weeks, the extent of vertical ridge resorption (VRR), bone density (density), new bone formation (NBF) and implant stability quotient (ISQ) were measured. Following systemic Vit.D/Ca administration, the Empty subgroup showed significant differences from the Calcitriol + Alloplast subgroup on variants NBF/Density/VRR and the Alloplast subgroup on items NBF/Density/ISQ/VRR. Alternatively, the Calcitriol + Alloplast subgroup revealed higher values of NBF/Density/ISQ (P < 0.001) and a lower VRR value (P = 0.001) than the Alloplast subgroup. Although there were no significant differences in NBF (P = 0.349), density (P = 0.796), ISQ (P = 0.577) and VRR (0.979) comparisons on alloplast treatment between the Vit.D/Ca and Non-Vit.D/Ca groups, local application with Calcitriol + Alloplast demonstrated better NBF/Density/ISQ (P = 0.02 to <0.001) effects than which of Alloplast subgroups. Consequently, the results showed that both syste...Continue Reading

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Citations

Mar 24, 2016·Journal of Applied Oral Science : Revista FOB·Suzana Peres PimentelMarcio Zaffalon Casati
Apr 6, 2017·BioMed Research International·Aileen I TsaiTzung-Hai Yen
Nov 27, 2016·International Journal of Implant Dentistry·Tobias FretwurstWiebke Semper-Hogg
Apr 30, 2021·Saudi Journal of Biological Sciences·Archana A GuptaShankargouda Patil
Jun 1, 2021·Curēus·Georgios MarkopoulosVasileios S Nikolaou

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