Association of weight change in different periods of adulthood with risk of type 2 diabetes in Japanese men and women: the Japan Public Health Center-Based Prospective Study

Journal of Epidemiology and Community Health
Akiko NanriJapan Public Health Center-based Prospective Study Group

Abstract

Few studies have examined the impact of weight change in different periods of lifetime on type 2 diabetes risk, and the association of weight loss with type 2 diabetes is unclear. We prospectively investigated the association of weight change since age 20 y and that during middle-to-late adulthood with the incidence of type 2 diabetes. Subjects were 52,014 men and women aged 45-75 y who participated in the Japan Public Health Center-Based Prospective Study and had no history of diabetes. ORs of self-reported physician-diagnosed type 2 diabetes for weight change between age 20 y and baseline survey (mean age 50.6 y) and during 5 y between baseline and second surveys were estimated using logistic regression analysis. During the 5-year period following 5-year survey, 989 newly diagnosed cases of type 2 diabetes were self-reported. Weight gain from age 20 y was associated with an increased risk of type 2 diabetes. The multivariate-adjusted OR (95% CI) for a weight gain of ≥5 kg versus a stable weight were 2.61 (2.11 to 3.23) in men and 2.56 (1.95 to 3.35) in women. A weight gain of ≥5 kg over the 5-y following the baseline survey was also associated with an increased risk in women. No association with weight loss was observed for e...Continue Reading

Citations

Dec 6, 2012·Epidemiology·Samuel H PrestonAndrew Stokes
Oct 5, 2013·BMC Endocrine Disorders·Ritsuko Yamamoto-HondaMitsuhiko Noda
Apr 1, 2015·Clinical Obesity·Y IbeH Sone
Oct 30, 2013·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S KodamaH Sone
Jul 29, 2015·BMC Public Health·Yoshihiko ManoZentaro Yamagata
Oct 22, 2013·Diabetes Research and Clinical Practice·Chie KanetoYasuki Kobayashi
Oct 16, 2012·International Journal of Cardiology·Sen HeKai Liu
Jun 28, 2016·European Journal of Gastroenterology & Hepatology·Yoshitaka HashimotoMichiaki Fukui
Apr 28, 2012·Geriatrics & Gerontology International·Yukio YoshimuraUNKNOWN Japanese Elderly Diabetes Intervention Trial Study Group
Aug 2, 2013·Epidemiology·Satoru KodamaHirohito Sone

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