Association study of bipolar disorder with candidate genes involved in catecholamine neurotransmission: DRD2, DRD3, DAT1, and TH genes

American Journal of Medical Genetics
D SoueryJ Mendlewicz

Abstract

Despite strong evidence for genetic involvement in the etiology of affective disorders (from twin adoption and family studies), linkage and association methodologies are still exploring the nature of genetic factors in these diseases. Interesting testable hypotheses have been described, including candidate genes involved in catecholamine neurotransmission. We studied 69 bipolar patients and 69 matched controls (for age, sex, and geographical origin) for association and linkage disequilibrium with DNA markers at the following genes: the tyrosine hydroxylase gene, dopamine transporter gene, and dopamine D2 and D3 receptor genes. Association and linkage disequilibrium were excluded between bipolar affective disorder and these four candidate genes in our sample.

References

May 1, 1992·Journal of Affective Disorders·P MitchellJ Shine
May 1, 1991·The British Journal of Psychiatry : the Journal of Mental Science·D HolmesH Gurling
Dec 1, 1991·The American Journal of Psychiatry·J MendlewiczJ Mallet
Jan 1, 1991·Journal of Psychiatric Research·M GillR M Murray
Jul 11, 1991·Nucleic Acids Research·M H PolymeropoulosC R Merril
Nov 1, 1965·The American Journal of Psychiatry·J J Schildkraut
Jun 19, 1995·American Journal of Medical Genetics·A ParsianR D Todd
Dec 15, 1994·American Journal of Medical Genetics·D E Comings
Apr 1, 1993·Journal of Medical Genetics·S ShaikhM Gill
Jul 15, 1993·American Journal of Medical Genetics·Y InayamaH Asaba
Jul 15, 1993·American Journal of Medical Genetics·R R Crowe
Aug 1, 1993·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·P V GejmanE S Gershon

❮ Previous
Next ❯

Citations

Jul 1, 1998·Environmental Health Perspectives·M A Rossing
Jul 10, 2013·European Psychiatry : the Journal of the Association of European Psychiatrists·Y-S WangR-B Lu
Apr 30, 2008·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Jiajun ShiChunyu Liu
Apr 20, 2012·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Chih-Chun HuangRu-Band Lu
May 11, 2012·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Fayaz SeifuddinPeter P Zandi
Nov 20, 2009·Bipolar Disorders·David A CousinsAllan H Young
Aug 29, 2006·Biological Psychiatry·Ari A GershonLeon Grunhaus
Aug 11, 2012·Progress in Neuro-psychopharmacology & Biological Psychiatry·Sheng-Yu LeeRu-Band Lu
Dec 31, 2014·European Archives of Psychiatry and Clinical Neuroscience·Chang-Chih HuangSan-Yuan Huang
Dec 7, 2010·Journal of Affective Disorders·Yan-Feng ZouFen Huang
Nov 16, 2013·The International Journal of Neuropsychopharmacology·Tzu-Yun WangRu-Band Lu
Jun 1, 1999·Acta Neuropsychiatrica·D Souery, J Mendlewicz
Feb 25, 2000·American Journal of Medical Genetics·A S HendersonS Easteal
May 29, 2002·European Journal of Human Genetics : EJHG·Jurgen Del-FaveroChristine Van Broeckhoven
May 7, 2002·American Journal of Medical Genetics·Cristina CusinEnrico Smeraldi
Dec 24, 2002·American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics : the Official Publication of the International Society of Psychiatric Genetics·Ernest P Noble
Aug 19, 2006·Human Mutation·Ann Van Den BogaertChristine Van Broeckhoven
Mar 30, 2007·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Regina HünnerkopfKlaus Peter Lesch
Jun 26, 2010·Pharmacogenetics and Genomics·Sheng-Yu LeeRu-Band Lu
Sep 22, 1999·American Journal of Medical Genetics·A SerrettiE Smeraldi
Mar 20, 2001·Bipolar Disorders·J B Potash, J R DePaulo
Aug 12, 2010·The World Journal of Biological Psychiatry : the Official Journal of the World Federation of Societies of Biological Psychiatry·Sheng-Yu LeeRu-Band Lu

❮ Previous
Next ❯

Related Concepts

Related Feeds

Bipolar Disorder

Bipolar disorder is characterized by manic and/or depressive episodes and associated with uncommon shifts in mood, activity levels, and energy. Discover the latest research this illness here.