Associations Among Plasma Stress Markers and Symptoms of Anxiety and Depression in Patients with Breast Cancer Following Surgery

Psychiatry Investigation
Hyun-Bin JuDo-Un Jung

Abstract

The objective of present study is to analyze the prevalence of depression and anxiety following breast cancer surgery and to assess the factors that affect postoperative psychological symptoms. The Hamilton Rating Scale for Depression (HAM-D), Hamilton Anxiety Rating Scale (HAM-A), Body Image Scale (BIS), and Rosenberg Self Esteem Scale (RSES) were used to assess the psychological states of patients who had been diagnosed with and had undergone surgery for breast cancer. Blood concentrations of the stress markers adrenocorticotropic hormone, cortisol, arginine-vasopressin, and angiotensin-converting enzyme were measured. Pearson's correlation analysis and multilinear regression analysis were used to analyse the data. At least mild depressive symptoms were noted in 50.5% of patients, while 42.4% of patients exhibited at least mild anxiety symptoms. HAM-D score was positively correlated with HAM-A (r=0.83, p<0.001) and BIS (r=0.29, p<0.001) scores and negatively correlated with RSES score (r=-0.41, p<0.001). HAM-A score was positively correlated with BIS score (r=0.32, p<0.001) and negatively correlated with RSES score (r=-0.27, p<0.001). There were no statistically significant associations between stress markers and depression/a...Continue Reading

References

Jul 1, 1994·Journal of Psychiatric Research·I HeuserF Holsboer
Nov 1, 1993·The American Journal of Psychiatry·S C RibeiroJ F Greden
Apr 22, 1999·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·A HallL Fallowfield
Feb 13, 2001·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·P HopwoodS Al Ghazal
Mar 20, 2001·Journal of Clinical Psychology·S L ShapiroS F Kurker
Mar 26, 2003·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·R H OsborneJ L Hopper
Jan 1, 1959·The British Journal of Medical Psychology·M HAMILTON
Feb 1, 1960·Journal of Neurology, Neurosurgery, and Psychiatry·M HAMILTON
Sep 26, 2003·Psychosomatic Medicine·Laura S PorterMary Scott Soo
Oct 30, 2004·Psychoneuroendocrinology·Deborah E PolkClemens Kirschbaum
Feb 8, 2005·BMJ : British Medical Journal·Caroline BurgessAmanda Ramirez
Oct 18, 2005·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Floortje MolsLonneke V van de Poll-Franse
Nov 16, 2005·Psycho-oncology·Pat FobairJoan R Bloom
Feb 7, 2006·European Psychiatry : the Journal of the Association of European Psychiatrists·B E Leonard
Jun 2, 2006·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Elisabeth AndritschHellmut Samonigg
Jun 26, 2007·Progress in Neuro-psychopharmacology & Biological Psychiatry·Haldun SoygurIsmail Hakki Ayhan
Feb 23, 2008·General Hospital Psychiatry·Jesse R FannJulie Gralow
Dec 25, 2009·European Journal of Cancer Care·A HinzR Schwarz
May 8, 2010·Journal of Psychiatric Research·Michael RiedelFlorian Seemüller
Jun 22, 2010·Cancer·Christian A Falk DahlAlv A Dahl
Aug 19, 2010·International Journal of Methods in Psychiatric Research·Louis S MatzaDouglas Feltner
Oct 12, 2013·CA: a Cancer Journal for Clinicians·Carol DeSantisAhmedin Jemal

❮ Previous
Next ❯

Citations

Sep 25, 2019·Healthcare·Milena B IlicDalibor V Jovanovic
Jan 18, 2020·Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research·Peirong LiuSheng Peng
Apr 29, 2020·Supportive Care in Cancer : Official Journal of the Multinational Association of Supportive Care in Cancer·Deepti ChopraTamara E Lacourt
Mar 7, 2021·International Journal of Environmental Research and Public Health·Tso-Ying LeeChin-Ching Li
Apr 30, 2021·Psychogeriatrics : the Official Journal of the Japanese Psychogeriatric Society·Yan SunJunping Bian
Aug 2, 2021·Journal of Pain and Symptom Management·Christine MiaskowskiJon D Levine

❮ Previous
Next ❯

Methods Mentioned

BETA
biopsy

Software Mentioned

SPSS

Related Concepts

Related Feeds

Body Dysmorphic Disorder

Body dysmorphic disorder is an intense preoccupation with an imagined defect in ones physical appearance. It can be a severely impairing disorder and is common among patients with obsessive-compulsive disorder. Discover the latest research on body dysmorphic disorder here.