PMID: 8968853Dec 1, 1996Paper

Associations between 12 year changes in body fatness and lipoprotein-lipid levels in men and women of the Québec Family Study

International Journal of Obesity and Related Metabolic Disorders : Journal of the International Association for the Study of Obesity
Charles CouillardJ P Després

Abstract

To investigate the associations between 12 year changes in body composition, subcutaneous fat distribution vs changes in plasma lipoprotein-lipid levels. 12 year prospective study. A sample of 95 women and 93 men of the Québec Family Study initially tested in 1980. Various body fatness variables as well as fasting plasma lipoprotein-lipid concentrations performed both in 1980 and 1992. In both 1980 and 1992, a high body fat mass and an elevated accumulation of subcutaneous trunk fat were associated with a significant deterioration in the plasma lipoprotein-lipid profile. Furthermore, correlation analysis performed on differences noted during the 12 years follow-up revealed significant associations between changes in body fat mass and in plasma cholesterol [r = 0.52, P < 0.0005] in women. In both men and women, an increased body fat mass was associated with an increased CHOL/HDL-cholesterol ratio [r = 0.37, P < 0.01 (men) and r = 0.54, P < 0.0005 (women)]. Correlations between changes in fat mass and plasma lipids were generally of higher magnitude in women than in men. Changes in subcutaneous trunk fat were associated with changes in plasma HDL-chol levels (r = -0.22, P < 0.05) in men whereas in women, changes in trunk adiposit...Continue Reading

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