PMID: 9159597Apr 1, 1997Paper

Associations between atrial natriuretic peptides, echocardiographic findings and mortality in an elderly population sample

Journal of Internal Medicine
A M IivanainenM Kupari

Abstract

To examine associations of N-terminal and C-terminal components of the proatrial natriuretic peptide [ANP (1-98) and ANP (99-126), respectively], with echocardiographic measurements of left ventricular structure and performance and with the function of the aortic and mitral valves in old age. To compare the predictive value of the atrial peptides and echocardiographic data for short-term mortality. A population based survey with 1.5-year mortality follow-up. University hospital. Three-hundred and thirty-three people aged 78-88 years. (i) Plasma ANP (1-98) and ANP (99-126); (ii) M-mode and Doppler echocardiographic measurements of left atrial diameter; left ventricular diameters, mass and fractional shortening; peak transmitral velocities; aortic valve area, aortic regurgitation jet length and mitral regurgitant jet area; (iii) total and cardiovascular 1.5-year mortality. ANP (1-98) correlated with left atrial diameter (r = 0.33; P < 0.001), left ventricular mass (r = 0.19; P < 0.001), fractional shortening (r = -0.16; P < 0.01) and the early-to-atrial peak transmitral velocity ratio (r = 0.23; P < 0.001). Also, ANP (1-98) predicted the degree of aortic valve obstruction and the severity of aortic and mitral regurgitation. Assoc...Continue Reading

Citations

Oct 2, 2004·International Journal of Cardiology·Paavo UusimaaUNKNOWN Anglo-Scandinavian Cardiac Outcomes Trial Investigators
May 3, 2003·International Journal of Cardiology·K W E GroundstroemA J Uusitalo
Nov 7, 2003·International Journal of Cardiology·Motoyuki Nakamura, Katsuhiko Hiramori
Feb 13, 2001·European Journal of Heart Failure·R KlemolaM Laine
May 17, 2012·Journal of the American Geriatrics Society·Mads NyboKaren Andersen-Ranberg
Aug 13, 2015·Disease Markers·Abhishek SharmaChirag Aggarwal
Jan 22, 2002·Best Practice & Research. Clinical Endocrinology & Metabolism·E S Nylén, A A Alarifi
Sep 13, 2002·Microscopy Research and Technique·Magnus Hansson
Jun 6, 2003·Endocrine Reviews·Heikki Ruskoaho
Feb 1, 2003·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Ingegerd Odar-CederlöfCarl M Kjellstrand

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