Associations Between Day-by-Day Home Blood Pressure Variability and Renal Function and Albuminuria in Patients With and Without Diabetes.

American Journal of Hypertension
Daisuke SuzukiKazuomi Kario

Abstract

The phenotype of diabetic kidney disease represents a lower estimated glomerular filtration rate (eGFR) and albuminuria. We investigated the association between day-by-day home blood pressure (BP) variability and the eGFR in subjects with diabetes and compared this association with that in subjects without diabetes. We then attempted to determine whether the association is present in albuminuria. We analyzed 4,231 patients with risk factors of cardiovascular disease (24.4% with diabetes) from the J-HOP (Japan Morning Surge-Home Blood Pressure) study. Home BP was measured in the morning and evening for 14 days. We calculated the SD, coefficient of variation, average real variability (ARV), and variation independent of the mean of the subjects' morning and evening home systolic BP (SBP) as the indexes of day-by-day home BP variability. A multiple linear regression analysis adjusted for covariates showed both average morning and evening SBP were associated with the log-transformed urine albumin-to-creatinine ratio (UACR) with and without diabetes (all P < 0.05), but not with the eGFR except for an association of average evening SBP in the no-diabetes group. None of the indexes of day-by-day morning and evening home SBP variability...Continue Reading

References

Jun 1, 1996·Kidney International·B M BrennerH S Mackenzie
Nov 19, 2003·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Yutaka ImaiUNKNOWN Japanese Society of Hypertension
Apr 13, 2006·JAMA : the Journal of the American Medical Association·Louis MonnierClaude Colette
Aug 5, 2011·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Emi UshigomeNaoto Nakamura
Aug 17, 2011·Nephron. Experimental Nephrology·Ahmed H AbdelhafizMeguid El Nahas
Dec 21, 2011·Blood Pressure Monitoring·Tomonari OkadaToshiyuki Nakao
Apr 6, 2012·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Satoshi HoshideKazuomi Kario
Apr 5, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Motonobu NishimuraYoshiharu Hoshiyama
Oct 2, 2013·Clinical and Experimental Nephrology·Miho ShimizuTakashi Wada
Nov 6, 2013·Nature Reviews. Nephrology·Kazuomi Kario
Jan 30, 2014·American Journal of Hypertension·Satoshi HoshideUNKNOWN J-HOP Study Group
May 2, 2014·Advances in Chronic Kidney Disease·Sally M Marshall
Dec 5, 2014·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Chikara NakanoIchiro Shiojima
Nov 11, 2015·Nature Reviews. Nephrology·Merlin C ThomasPaul Zimmet
Oct 23, 2016·Trends in Endocrinology and Metabolism : TEM·Luigi GnudiDavid A Long
Aug 18, 2016·JAMA : the Journal of the American Medical Association·Maryam AfkarianIan H de Boer
Aug 26, 2016·American Journal of Physiology. Renal Physiology·Raimund PichlerKatherine R Tuttle
Jan 18, 2017·Journal of Diabetes Investigation·Yosuke HirakawaMasaomi Nangaku
Feb 15, 2017·Hypertension·Eeva P JuhanojaUNKNOWN International Database on Home Blood Pressure in Relation to Cardiovascular Outcome (IDHOCO) Investigators
Sep 16, 2017·American Journal of Hypertension·Shinobu MatsumotoMichiaki Fukui
Aug 4, 2019·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Satoshi UmemuraNobuhito Hirawa

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Citations

Dec 1, 2020·American Journal of Hypertension·Satoshi HoshideKazuomi Kario
Aug 26, 2021·American Journal of Hypertension·Kazuomi Kario
Oct 16, 2021·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Masaki MogiKazuomi Kario
Dec 23, 2021·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Takuro KubozonoMitsuru Ohishi

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