Associations between dry dietary factors and canine calcium oxalate uroliths

American Journal of Veterinary Research
C LekcharoensukL L Swanson

Abstract

To identify factors in dry diets associated with the occurrence of calcium oxalate (CaOx) uroliths in dogs. 600 dogs with CaOx uroliths and 898 dogs without urinary tract diseases. Univariate and multivariate logistic regression were performed. Compared with diets with the highest concentrations of sodium, dry diets with the lowest concentrations of sodium, phosphorus, calcium, chloride, protein, magnesium, or potassium were linearly associated with increased risk of CaOx urolith formation. Significant nonlinear associations between increased occurrence of CaOx uroliths and urine acidifying potential and low moisture content were observed. Significant nonlinear associations between decreased occurrence of CaOx uroliths and carbohydrate and fiber contents were observed. A significant association between the occurrence of CaOx uroliths and dietary fat was not observed. Results suggest that dry diets formulated to contain high concentrations of protein, calcium, phosphorus, magnesium, sodium, potassium, and chloride may minimize formation of CaOx uroliths. In addition, comparison of risk and protective factors of various diet ingredients fed to dogs with CaOx uroliths suggests that although similar findings were observed in canned...Continue Reading

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Citations

Dec 17, 2008·Journal of Feline Medicine and Surgery·Hui XuGrace L Long
Nov 29, 2008·The Veterinary Clinics of North America. Small Animal Practice·Carl A OsborneHasan Albasan
Apr 20, 2005·The Journal of Small Animal Practice·M SosnarM Ruzicka
Sep 10, 2016·Journal of Veterinary Internal Medicine·J P LulichC A Osborne
Nov 23, 2016·Journal of the American Veterinary Medical Association·Stephanie M KennedyEva Furrow
Nov 8, 2020·Nature Reviews. Urology·Ashley AlfordJody Lulich
Feb 12, 2013·The Veterinary Record·J P LulichC Lekcharoensuk
May 8, 2021·Journal of Veterinary Internal Medicine·Lucy KopecnyJodi L Westropp

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