Associations between mortality, asthma, and health-related quality of life in an elderly cohort of Swedes

The Journal of Asthma : Official Journal of the Association for the Care of Asthma
Mai LeanderAnna Rask-Andersen

Abstract

Asthma is a common chronic health condition among the elderly and an important cause of morbidity and mortality. Some studies show that subjective assessments of health-related quality of life (HRQL) are important predictors of mortality and survival. The primary aim of this study was to investigate whether low HRQL was a predictor of mortality in elderly subjects and whether such an association differed between subjects with and without asthma. In 1990, a cohort in middle Sweden was investigated using a respiratory questionnaire. To assess HRQL, the generic instrument Gothenburg Quality of Life (GQL) was used. The participants were also investigated by spirometry and allergy testing. The present study was limited to the subjects in the oldest age group, aged 60-69 years in 1990, and included 222 subjects with clinically verified asthma, 148 subjects with respiratory symptoms but no asthma or other lung diseases, and 102 subjects with no respiratory symptoms. Mortality in the cohort was followed during 1990-2008. Altogether, 166 of the 472 subjects in the original cohort had died during the follow-up period of 1990-2008. Mortality was significantly higher in men, in older subjects, in smokers, and subjects with a low forced exp...Continue Reading

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Citations

Feb 18, 2012·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kathleen M AkgünMargaret Pisani
Feb 26, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Jacqueline A RossAlan P Baptist

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