Associations between outdoor temperature and markers of inflammation: a cohort study.

Environmental Health : a Global Access Science Source
Jaana I HalonenJoel Schwartz

Abstract

Associations between ambient temperature and cardiovascular mortality are well established. This study investigated whether inflammation could be part of the mechanism leading to temperature-related cardiovascular deaths. The study population consisted of a cohort of 673 men with mean age of 74.6 years, living in the greater Boston area. They were seen for examination roughly every 4 years, and blood samples for inflammation marker analyses were drawn in 2000-2008 (total of 1254 visits). We used a mixed effects model to estimate the associations between ambient temperature and a variety of inflammation markers (C-reactive protein, white blood cell count, soluble Vascular Cell Adhesion Molecule-1, soluble Intercellular Adhesion Molecule-1, tumor necrosis factor alpha, and interleukins -1beta, -6 and -8). Random intercept for each subject and several possible confounders, including combustion-related air pollution and ozone, were used in the models. We found a 0 to 1 day lagged and up to 4 weeks cumulative responses in C-reactive protein in association with temperature. We observed a 24.9% increase [95% Confidence interval (CI): 7.36, 45.2] in C-reactive protein for a 5 degrees C decrease in the 4 weeks' moving average of tempera...Continue Reading

References

Feb 1, 1993·American Journal of Epidemiology·A E KunstJ P Mackenbach
Aug 1, 1996·Arteriosclerosis, Thrombosis, and Vascular Biology·J GaleaC M Holt
Nov 15, 1996·Biochimica Et Biophysica Acta·A Koj
Apr 3, 1997·The New England Journal of Medicine·P M RidkerC H Hennekens
Jan 5, 2002·American Journal of Epidemiology·Frank C CurrieroJonathan A Patz
Aug 15, 2002·Circulation·Christie M Ballantyne, Mark L Entman
Jun 19, 2003·The Journal of Clinical Investigation·Mark B Pepys, Gideon M Hirschfield
May 13, 2005·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Marie S O'NeillJoel Schwartz
Nov 19, 2005·American Journal of Respiratory and Critical Care Medicine·Regina RückerlAnnette Peters
Dec 17, 2005·Epidemiology·Alain Le TertreMartine Ledrans
Aug 15, 2006·BJOG : an International Journal of Obstetrics and Gynaecology·R Cancello, K Clément
Apr 28, 2007·American Journal of Respiratory and Critical Care Medicine·Kai-Jen ChuangChin-Sheng Tang
Jun 30, 2007·Occupational and Environmental Medicine·M Medina-Ramón, J Schwartz
Oct 5, 2007·Environmental Research·Arie SteinvilOri Rogowski
Apr 17, 2008·Epidemiology·Alexandra SchneiderUNKNOWN AIRGENE Study Group
Jun 5, 2008·International Journal of Epidemiology·Anthony J McMichaelBojidar Nikiforov
Apr 25, 2009·Arquivos brasileiros de cardiologia·Adriane M RamosVera L Portal
Apr 28, 2009·Environmental Research·Bart D OstroRupa Basu
Jun 26, 2009·PLoS Medicine·Naveed SattarUNKNOWN Prospective Study of Pravastatin in the Elderly at Risk (PROSPER) Study Group
Jul 11, 2009·Environmental Health Perspectives·Goran RudezMoniek P M de Maat
Aug 19, 2009·Circulation·Kathrin WolfUNKNOWN Cooperative Health Research in the Region of Augsburg Study Group
Aug 22, 2009·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·B G Nordestgaard, J Zacho
Sep 26, 2009·Journal of the American College of Cardiology·Mary M McDermott, Donald M Lloyd-Jones
Oct 7, 2009·Advances in Clinical Chemistry·Carita M Eklund
Nov 4, 2009·Occupational and Environmental Medicine·Jaime MadriganoJoel Schwartz
Nov 4, 2009·Occupational and Environmental Medicine·Regina HampelAlexandra Schneider
Mar 12, 2010·Environmental Health : a Global Access Science Source·Sofia P AlmeidaJosé Calheiros

❮ Previous
Next ❯

Citations

May 17, 2012·Environmental Health Perspectives·Elissa H WilkerMurray A Mittleman
Sep 19, 2012·Journal of the American Medical Directors Association·Pui Hing ChauJean Woo
Oct 29, 2014·ANZ Journal of Surgery·Robert E BrightwellPhilip J Walker
Oct 3, 2012·International Journal of Occupational and Environmental Health·Shao LinSyni-An Hwang
Dec 22, 2010·Environmental Research·Jaana I HalonenJoel Schwartz
Dec 3, 2014·Journal of Epidemiology and Community Health·Antonella Zanobetti, Annette Peters
May 3, 2016·International Journal of Environmental Research and Public Health·Chisato ImaiYasushi Honda
Jun 14, 2016·The Science of the Total Environment·Jing CaiHaidong Kan
Oct 17, 2016·The Science of the Total Environment·Daisuke Onozuka, Akihito Hagihara
Dec 22, 2016·Journal of the Air & Waste Management Association·Antonella ZanobettiJoel Schwartz
Jan 21, 2017·Environmental Research·Adrian G BarnettMartin Wolkewitz
Dec 3, 2016·European Journal of Preventive Cardiology·Claudio SartiniRichard W Morris
Apr 22, 2017·International Journal of Environmental Research and Public Health·Suji Lee, Matthias Guth
May 19, 2017·Nature Reviews. Cardiology·Simon StewartJohn J V McMurray
Feb 24, 2017·Environmental Science and Pollution Research International·Laura TamasauskieneEgle Milinaviciene
Jun 18, 2017·Environmental Science & Technology·Cong LiuHaidong Kan
Jun 4, 2016·Environmental Health Perspectives·Yuming GuoShilu Tong
Mar 22, 2013·Journal of Toxicology and Environmental Health. Part a·Ana MendesJoão Paulo Teixeira
Oct 27, 2015·Environmental Research Letters : ERL [Web Site]·Patrick L KinneyRobert Vautard
Sep 7, 2011·Environmental Research Letters : ERL [Web Site]·Ji-Young SonMichelle L Bell
Jun 3, 2020·European Journal of Preventive Cardiology·Giuseppe Biondi-ZoccaiFrancesco Versaci
May 9, 2014·Epidemiology·Marie-Abele BindJoel Schwartz
Oct 28, 2019·Environmental Health Perspectives·Lindsey Konkel
Jun 15, 2020·BMC Cardiovascular Disorders·Brigitta SzilágyiPéter Sótonyi
Dec 7, 2016·International Journal of Biometeorology·Daisuke Onozuka, Akihito Hagihara
Feb 24, 2017·International Journal of Biometeorology·Giehae ChoiYoun-Hee Lim
Nov 7, 2019·Environmental Health Perspectives·Dries S MartensTim S Nawrot
Nov 13, 2018·Current Epidemiology Reports·Antonella Zanobetti, Marie S O'Neill
Jan 9, 2021·Environmental Health : a Global Access Science Source·Feiby L NassanJoel D Schwartz
Jan 16, 2021·The Science of the Total Environment·Hui HuJiang Bian

❮ Previous
Next ❯

Methods Mentioned

BETA
Enzyme-Linked Immunosorbent Assay
ELISA

Software Mentioned

R
mgcv
nlme

Related Concepts

Related Feeds

Antihypertensive Agents: Mechanisms of Action

Antihypertensive drugs are used to treat hypertension (high blood pressure) which aims to prevent the complications of high blood pressure, such as stroke and myocardial infarction. Discover the latest research on antihypertensive drugs and their mechanism of action here.

Cell Adhesion Molecules in AS

Cell adhesion molecules expressed on the vascular endothelium and circulating leukocytes in response to inflammatory stimuli are implicated in atherosclerosis. Here is the latest research.

Cardiovascular Inflammation

Inflammation plays a significant role in the development of cardiovascular diseases, an understanding of these endogenous processes is critical for evaluating the risks and potential treatment strategies. Discover the latest research on cardiovascular inflammation here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

© 2021 Meta ULC. All rights reserved