Associations between particulate matter air pollution, presence and progression of subclinical coronary and carotid atherosclerosis: A systematic review.

Atherosclerosis
Mohammad Hashim JilaniKhurram Nasir

Abstract

Long-term exposure to particulate matter (PM) air pollution has been linked with increased cardiovascular events and mortality, however, studies had shown inconsistent associations between PM exposure and subclinical atherosclerosis. We performed an updated systematic literature review to identify studies evaluating the associations between PM and subclinical atherosclerosis, measured using presence/progression of coronary artery calcium (CAC) or carotid intima-media thickness (CIMT) in adult populations. Quality was assessed using the Newcastle-Ottawa scale. Eighteen studies were included: 5 cohorts and 13 cross-sectional. Amongst 7 studies that evaluated the associations between PM and prevalence of CAC, 4 reported significantly higher odds of detectable CAC>0 or CAC>400 with increased PM exposure. Nine studies evaluated the association between exposure to at least one of the particulates and CIMT; of these, 6 reported significant independent associations. Two studies evaluated PM2.5 and CAC progression, with 1 reporting a greater progression of CAC with increased exposure to PM, while 3 out of 4 studies evaluating CIMT progression showed no significant difference in CIMT progression with a higher PM2.5 exposure. Additionally...Continue Reading

Citations

Feb 6, 2021·Environmental Science and Pollution Research International·Karen HettfleischLisandra Stein Bernardes
Jul 27, 2021·Current Atherosclerosis Reports·Mohammad Hashim JilaniKhurram Nasir
Aug 18, 2021·International Journal of Hygiene and Environmental Health·Chieh-Ming WuChi Song

❮ Previous
Next ❯

Related Concepts

Related Feeds

Carotid Artery Diseases

Carotid artery disease is a group of pathological conditions of the carotid artery. Discover the latest research on carotid artery disease here.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.

Atherosclerosis Disease Progression

Atherosclerosis is the buildup of plaque on artery walls, causing stenosis which can eventually lead to clinically apparent cardiovascular disease. Find the latest research on atherosclerosis disease progression here.