PMID: 2502494Apr 1, 1989Paper

Associations between serotype and susceptibility to antibiotics of Neisseria gonorrhoeae

Genitourinary Medicine
N WoodfordC A Ison

Abstract

A serological classification scheme for Neisseria gonorrhoeae was used to investigate the epidemiological associations between gonococcal serotype and other bacterial and host characters. Six hundred and fifty clinical isolates of non-penicillinase producing N gonorrhoeae from the Praed Street Clinic, St Mary's Hospital, were included in this study. The strains collected represented 41 serovars, although 485 (75%) of the 650 strains belonged to five serovars. Strains of serovar IA-1/2 were commonly isolated from the cervix and tended to be sensitive to penicillin and moderately resistant to erythromycin. Strains of serovar IB-1 showed bimodal patterns of susceptibility to both penicillin and erythromycin and were obtained equally from all anatomical sites. Strains of serovar IB-2 were isolated more often from the rectum and were associated with homosexually acquired infections, whereas those of serovar IB-3 were sensitive to erythromycin and were rarely isolated from the rectum. Strains of IB-5/7 were more resistant to penicillin and erythromycin than strains of other serovars. The serological classification of N gonorrhoeae is thus a powerful tool that may be used to study biological characteristics of the gonococcus, such as ...Continue Reading

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Citations

Apr 1, 1995·Antimicrobial Agents and Chemotherapy·J R SchwebkeK K Holmes
Apr 1, 1990·Genitourinary Medicine·C A IsonN Woodford
Oct 1, 1990·Genitourinary Medicine·C A IsonC S Easmon
Aug 1, 1991·Genitourinary Medicine·C A Ison, C S Easmon
Aug 1, 1991·Genitourinary Medicine·H YoungA McMillan
Oct 1, 1991·Genitourinary Medicine·C L PohS M Bygdeman
Dec 1, 1994·Genitourinary Medicine·J D Ross, H Young
Dec 2, 2005·Dermatology : International Journal for Clinical and Investigative Dermatology·Shahnaz AbrahamVincent Piguet
May 1, 1992·Medical Anthropology·R Bolton
Aug 1, 1989·Epidemiology and Infection·K M Bindayna, C A Ison

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