Associations between urinary concentrations of 2,5-dichlorophenol and metabolic syndrome among non-diabetic adults

Environmental Science and Pollution Research International
Yudan Wei, Jianmin Zhu

Abstract

We investigated in this study the relationship between exposure to para-dichlorobenzene (p-DCB), measured as urinary concentrations of 2,5-dichlorophenol (2,5-DCP), and metabolic syndrome in non-diabetic adult participants. A nationally representative subsample of 1706 non-diabetic adult participants aged 20-79 years randomly selected for measurement of urinary concentrations of 2,5-DCP in the 2007-2010 US National Health and Nutrition Examination Survey was analyzed. A dose-dependent increase in the prevalence of metabolic syndrome was observed in the study participants across quartiles of urinary 2,5-DCP (p-trend = 0.0025). After adjusting for potential confounders, individuals in the third and fourth quartile of urinary 2,5-DCP had 1.47 (95% CI 1.02, 2.14) and 1.56 (95% CI 1.10, 2.23) increased odds of metabolic syndrome, respectively, compared with individuals with the lowest quartile. Of the five components of metabolic syndrome, waist circumference and HDL-cholesterol showed a significant and monotonic association with urinary 2,5-DCP. Participants with the highest quartile of 2,5-DCP had 3.18 cm (95% CI 1.34, 5.02) higher mean waist circumference and 2.83 mg/dL (95% CI -4.68, -0.98) lower mean HDL-cholesterol than the pa...Continue Reading

References

May 11, 2002·Environmental Health Perspectives·Jane A HoppinDonna D Baird
May 15, 2002·The Journal of Alternative and Complementary Medicine : Research on Paradigm, Practice, and Policy·Paula F Baillie-Hamilton
Oct 26, 2002·Archives of Environmental Contamination and Toxicology·T YoshidaM Fukuhara
Mar 8, 2003·International Journal of Hygiene and Environmental Health·Kerstin BeckerBernd Seifert
Sep 29, 2004·Diabetes Care·Earl S FordAli H Mokdad
Nov 24, 2004·International Archives of Occupational and Environmental Health·Y SaijoT Umemura
Jan 22, 2011·The Journal of Steroid Biochemistry and Molecular Biology·Amanda Janesick, Bruce Blumberg
May 13, 2011·Environmental Health Perspectives·Anne RiuPatrick Balaguer
Dec 31, 2011·Reviews on Environmental Health·Claudia Twum, Yudan Wei
Feb 3, 2012·Environmental Health Perspectives·Kristina A ThayerMichael A Gallo
Feb 3, 2012·Environmental Health Perspectives·Wendee Holtcamp
Oct 2, 2012·Journal of the Air & Waste Management Association·Priscilla A Guerrero, Richard L Corsi
Nov 6, 2012·Environmental Health Perspectives·Danielle E ButtkeColleen Martin
Jul 27, 2014·The Journal of Pediatrics·Melanie C BuserFranco Scinicariello
Aug 21, 2014·Environmental Science and Pollution Research International·K CroesW Baeyens
Sep 15, 2014·Molecular and Cellular Endocrinology·Amanda S JanesickBruce Blumberg
Apr 2, 2015·Journal of Exposure Science & Environmental Epidemiology·Yudan Wei, Jianmin Zhu

❮ Previous
Next ❯

Citations

Aug 2, 2016·The Journal of Pediatrics·Yudan Wei, Jianmin Zhu
Mar 29, 2018·International Journal of Environmental Research and Public Health·Hyejin Park, Kisok Kim
Dec 7, 2017·Environmental Science and Pollution Research International·Michael Hendryx, Juhua Luo
Dec 1, 2017·Environmental Science and Pollution Research International·Saeed ParastarRoya Kelishadi
Aug 31, 2020·Environmental Science and Pollution Research International·Moon Young SeoMi Jung Park
Jul 2, 2020·International Journal of Environmental Research and Public Health·Taro Matsuki The Japan Environment And Children's Study Jecs Group

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.