Associations between UVR exposure and basal cell carcinoma site and histology

Cancer Letters
Tracy J LovattR C Strange

Abstract

While sunlight is critical in basal cell carcinoma (BCC) pathogenesis the relationship between exposure and tumor site and histology is unclear. We determined if tumor site (trunk or head/neck) or histology (nodular or superficial) is determined by exposure pattern. In 66 cases with truncal and 362 patients with head/neck BCC at first presentation, average hours exposure/year, intermittency score, childhood sunburning and skin type were not significantly associated with tumor site or histology. However, often sunbathing was associated with a five-fold increased risk of truncal BCC. Average sunbathing score was significantly greater in 22 cases with truncal compared with 325 cases with head/neck nodular tumors and also in 44 cases with superficial truncal compared with superficial head/neck BCC. Thus, sunbathing determined tumor site but not histology.

References

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Citations

Dec 2, 2009·Molecular Cancer·Andrea WatsonDavid O Walterhouse
Oct 28, 2006·The Journal of Investigative Dermatology·Claudio PelucchiOncology Study Group of the Italian Group for Epidemiologic Research in Dermatology (GISED)
Jul 5, 2008·Medical Hypotheses·Murat Livaoğlu, Devrim Bektaş
Nov 14, 2006·Journal of the American Academy of Dermatology·Rachel E NealeAdèle C Green
Mar 3, 2010·International Journal of Cancer. Journal International Du Cancer·Naomi M Richmond-SinclairAdèle C Green
Mar 20, 2015·Photodermatology, Photoimmunology & Photomedicine·Mohammad KhalesiNHMRC Centre of Research Excellence in Sun and Health
Feb 22, 2017·The British Journal of Dermatology·J A C VerkouterenT Nijsten
Dec 7, 2018·Journal of the European Academy of Dermatology and Venereology : JEADV·J A C VerkouterenT Nijsten

Related Concepts

Abdomen
Pigmented Basal Cell Carcinoma
Cancer of Neck
Retrospective Studies
Malignant Neoplasm of Skin
Sunburn
Chest
Black Light, Ultraviolet

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