Associations of Age, BMI, and Years of Menstruation with Proximal Femur Strength in Chinese Postmenopausal Women: A Cross-Sectional Study

International Journal of Environmental Research and Public Health
Huili KangSu-Mei Xiao

Abstract

This study aimed to elucidate the associations of age, BMI, and years of menstruation with proximal femur strength in Chinese postmenopausal women, which may improve the prediction of hip fracture risk. A cross-sectional study was conducted in 1322 Chinese postmenopausal women recruited from communities. DXA images were used to generate bone mineral density (BMD) and geometric parameters, including cross-sectional area (CSA), outer diameter (OD), cortical thickness (CT), section modulus (SM), buckling ratio (BR) at the narrow neck (NN), intertrochanter (IT), and femoral shaft (FS). Relationships of age, BMI, and years of menstruation with bone phenotypes were analyzed with the adjustment of height, age at menarche, total daily physical activity, education, smoking status, calcium tablet intake, etc. Age was associated with lower BMD, CSA, CT, SM, and higher BR (p < 0.05), which indicated a weaker bone strength at the proximal femur. BMI and years of menstruation had the positive relationships with proximal femur strength (p < 0.05). Further analyses showed that the ranges of absolute value of change slope per year, per BMI or per year of menstruation were 0.14%-1.34%, 0.20%-2.70%, and 0.16%-0.98%, respectively. These results su...Continue Reading

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Citations

Dec 27, 2019·Menopause : the Journal of the North American Menopause Society·Ke PengUNKNOWN China Kadoorie Biobank Collaborative Group‡
Oct 31, 2019·Einstein·Kátia Josiany SeghetoGiana Zarbato Longo
Apr 29, 2020·Lipids in Health and Disease·Liying JiangAidong Liu
Aug 20, 2020·Revista da Escola de Enfermagem da U S P·Kátia Josiany SeghetoGiana Zarbato Longo
May 25, 2021·Frontiers in Cell and Developmental Biology·Luana Mordask BonettoRafaela Scariot

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Methods Mentioned

BETA
X-ray

Software Mentioned

HSA
SPSS
APEX
Hip Structure Analysis ( HSA )

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