Associations of Bariatric Interventions With Micronutrient and Endocrine Disturbances

JAMA Network Open
Nicholas L SynChin Hong Lim

Abstract

Few studies have described the longitudinal trajectories of serum levels of micronutrients whose deficiencies are associated with serious sequelae following bariatric procedures, such as anemia, osteoporotic fractures, and neuropathies. Furthermore, previous studies comparing laparoscopic sleeve gastrectomy (LSG) vs Roux-en-Y gastric bypass (LRYGB) or one-anastomosis gastric bypass (OAGB) procedures may have been limited by selection and confounding biases. To appraise the spectrum and temporal course of micronutrient deficiencies associated with bone metabolism and erythropoiesis after LSG vs OAGB or LRYGB procedures, using the propensity score as a balancing score. This prospective, longitudinal comparative effectiveness study was conducted at a high-volume bariatric unit in Singapore from September 1, 2008, to November 30, 2017, with a cutoff date for analysis of September 2018. Patients who underwent adjustable gastric banding, biliopancreatic diversion procedures, and intragastric balloon procedures were excluded. All other patients who underwent bariatric procedures were included. Data were analyzed from September 23 to 30, 2018. Serial assessment of 13 biochemical parameters at 12 time points for up to 5 years after bari...Continue Reading

References

Jun 22, 2000·The New England Journal of Medicine·K Benson, A J Hartz
Aug 22, 2001·JAMA : the Journal of the American Medical Association·J P IoannidisJ Lau
Apr 25, 2006·Annals of Surgery·Jason M JohnsonJohn M Kellum
Mar 27, 2009·Nutrition in Clinical Practice : Official Publication of the American Society for Parenteral and Enteral Nutrition·Annette von Drygalski, Deborah A Andris
Nov 6, 2010·The Journal of Clinical Endocrinology and Metabolism·David HeberUNKNOWN Endocrine Society
Nov 23, 2010·Obesity Surgery·Edo O AartsFrits J Berends
Oct 29, 2011·Obesity Surgery·Davide LomantoTran Binh Giang
Nov 5, 2011·Biometrics·Shaun R SeamanLeah Li
Jul 7, 2012·BMC Surgery·Nicole PechChristine Stroh
Nov 5, 2013·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Andreas AlexandrouIrene Lambrinoudaki
Mar 4, 2014·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Yeongkeun KwonRaul J Rosenthal
Apr 8, 2014·Obesity Surgery·P W J van RutteS W Nienhuijs
Sep 27, 2015·International Journal of Surgery·Piotr AdamczykWojciech Pluskiewicz
Oct 16, 2015·Obesity Surgery·Byung-Joon KoSeon Mee Kim
Feb 3, 2016·Metabolism: Clinical and Experimental·Marlene Toufic ChakhtouraGhada A El Hajj Fuleihan
Feb 21, 2016·Clinical Endocrinology·Mary O'Kane, Julian H Barth
Mar 31, 2016·Expert Review of Gastroenterology & Hepatology·Chin Hong LimSayeed Ikramuddin
May 6, 2016·Obesity Surgery·Xiao DuZhong Cheng
Jun 4, 2016·Surgical Laparoscopy, Endoscopy & Percutaneous Techniques·Abdulrahman S Al-Mulhim
Nov 5, 2016·BMJ : British Medical Journal·Catherine RousseauClaudia Gagnon
Apr 11, 2017·Surgery for Obesity and Related Diseases : Official Journal of the American Society for Bariatric Surgery·Julie ParrottLaura Greiman
Jun 13, 2017·The New England Journal of Medicine·UNKNOWN GBD 2015 Obesity CollaboratorsChristopher J L Murray
Dec 6, 2017·JAMA Internal Medicine·João DelgadoDavid Melzer
Feb 6, 2018·The Lancet. Diabetes & Endocrinology·Geltrude MingroneCarel W Le Roux
Sep 8, 2018·Obesity Surgery·Phong Ching LeeKwang Wei Tham

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Methods Mentioned

BETA
gastric bypass

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IPTW

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