Associations of polyunsaturated Fatty Acid intake with bone mineral density in postmenopausal women

Journal of Osteoporosis
Margaret HarrisTimothy Lohman

Abstract

A secondary analysis of cross-sectional data was analyzed from 6 cohorts (Fall 1995-Fall 1997) of postmenopausal women (n = 266; 56.6 ± 4.7 years) participating in the Bone Estrogen Strength Training (BEST) study (a 12-month, block-randomized, clinical trial). Bone mineral density (BMD) was measured at femur neck and trochanter, lumbar spine (L2-L4), and total body BMD using dual-energy X-ray absorptiometry (DXA). Mean dietary polyunsaturated fatty acids (PUFAs) intakes were assessed using 8 days of diet records. Multiple linear regression was used to examine associations between dietary PUFAs and BMD. Covariates included in the models were total energy intake, body weight at year 1, years after menopause, exercise, use of hormone therapy (HT), total calcium, and total iron intakes. In the total sample, lumbar spine and total body BMD had significant negative associations with dietary PUFA intake at P < 0.05. In the non-HT group, no significant associations between dietary PUFA intake and BMD were seen. In the HT group, significant inverse associations with dietary PUFA intake were seen in the spine, total body, and Ward's triangle BMD, suggesting that HT may influence PUFA associations with BMD. This study is registered with c...Continue Reading

Associated Clinical Trials

References

Feb 1, 1997·Journal of the American Dietetic Association·J L WeberT G Lohman
Feb 5, 1999·Aging : Clinical and Experimental Research·M C KrugerD H van Papendorp
Mar 16, 2000·Prostaglandins, Leukotrienes, and Essential Fatty Acids·C K SchlemmerM C Kruger
Jun 9, 2001·Experimental Biology and Medicine·B A WatkinsM F Seifert
Jul 19, 2002·JAMA : the Journal of the American Medical Association·Jacques E RossouwUNKNOWN Writing Group for the Women's Health Initiative Investigators
Nov 27, 2002·Journal of the American Dietetic Association·Paula TrumboUNKNOWN Food and Nutrition Board of the Institute of Medicine, The National Academies
Apr 18, 2003·European Journal of Clinical Nutrition·J Z IlichL Tamborini
Jun 12, 2003·Prostaglandins, Leukotrienes, and Essential Fatty Acids·R L Corwin
Jul 5, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Scott GoingJudith Weber
Sep 23, 2003·Menopause : the Journal of the North American Menopause Society·Ken D StarkBruce J Holub
Nov 11, 2003·The Journal of Nutrition·Margaret M HarrisTimothy G Lohman
Apr 9, 2005·The American Journal of Clinical Nutrition·Lauren A WeissDenise von Mühlen
Nov 12, 2005·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Ellen C CusslerTimothy G Lohman
Oct 19, 2006·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·A P Simopoulos
Oct 19, 2006·Clinical Nutrition : Official Journal of the European Society of Parenteral and Enteral Nutrition·Stephen J Genuis, Gerry K Schwalfenberg
Nov 25, 2011·European Journal of Clinical Nutrition·R JärvinenH Kröger
Oct 30, 2012·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A Casado-DíazJ M Quesada-Gómez
Jul 17, 2013·Current Osteoporosis Reports·Kelsey M ManganoMarian T Hannan
Dec 5, 2013·TheScientificWorldJournal·Naroa KajarabilleJulio J Ochoa
Jan 15, 2014·Prostaglandins, Leukotrienes, and Essential Fatty Acids·Charlene M SibbonsGraham C Burdge

❮ Previous
Next ❯

Citations

Jan 23, 2018·The British Journal of Nutrition·Leila Khorrami-NezhadSeyed Ali Keshavarz
Mar 17, 2016·Advances in Nutrition·Amanda B Longo, Wendy E Ward
Aug 17, 2018·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Aliyu MuhammadIbrahim Babangida Abubakar
Mar 12, 2021·The Journal of Clinical Endocrinology and Metabolism·Rui GongHong-Wen Deng

❮ Previous
Next ❯

Methods Mentioned

BETA
X-ray

Software Mentioned

Statistical Package for the Social Sciences ( SPSS

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA
M C WangJ L Kelsey
© 2021 Meta ULC. All rights reserved