Associations of pregnancy complications with calculated cardiovascular disease risk and cardiovascular risk factors in middle age: the Avon Longitudinal Study of Parents and Children.

Circulation
Abigail FraserDebbie A Lawlor

Abstract

The nature and contribution of different pregnancy-related complications to future cardiovascular disease (CVD) and its risk factors and the mechanisms underlying these associations remain unclear. We studied associations of pregnancy diabetes mellitus, hypertensive disorders of pregnancy, preterm delivery, and size for gestational age with calculated 10-year CVD risk (based on the Framingham score) and a wide range of cardiovascular risk factors measured 18 years after pregnancy (mean age at outcome assessment, 48 years) in a prospective cohort of 3416 women. Gestational diabetes mellitus was positively associated with fasting glucose and insulin, even after adjustment for potential confounders, whereas hypertensive disorders of pregnancy were associated with body mass index, waist circumference, blood pressure, lipids, and insulin. Large for gestational age was associated with greater waist circumference and glucose concentrations, whereas small for gestational age and preterm delivery were associated with higher blood pressure. The association with the calculated 10-year CVD risk based on the Framingham prediction score was odds ratio 1.31 (95 confidence interval, 1.11-1.53) for preeclampsia and 1.26 (95 confidence interval,...Continue Reading

References

Apr 1, 1988·American Journal of Obstetrics and Gynecology·D A Davey, I MacGillivray
Nov 24, 2001·BMJ : British Medical Journal·H U IrgensR T Lie
Jul 20, 2002·BMJ : British Medical Journal·Naveed Sattar, Ian A Greer
Jun 14, 2005·Epidemiology·George Davey SmithFinn Rasmussen
Dec 8, 2005·JAMA : the Journal of the American Medical Association·Risto J Kaaja, Ian A Greer
Nov 3, 2007·BMJ : British Medical Journal·Leanne BellamyDavid J Williams
Jan 24, 2008·Circulation·Ralph B D'AgostinoWilliam B Kannel
May 9, 2008·The New England Journal of Medicine·UNKNOWN HAPO Study Cooperative Research GroupDavid A Sacks
Feb 20, 2010·Obstetrics and Gynecology·Elisabeth B MagnussenPål R Romundstad
Jul 28, 2010·Circulation·Pål R RomundstadLars J Vatten

❮ Previous
Next ❯

Citations

Apr 18, 2012·International Journal of Epidemiology·Abigail FraserDebbie A Lawlor
Apr 4, 2013·Menopause : the Journal of the North American Menopause Society·José T DrostAngela H E M Maas
Aug 29, 2013·Menopause : the Journal of the North American Menopause Society·Nandita S Scott
Nov 14, 2013·PloS One·Elani StrejaJørn Olsen
Aug 31, 2013·Journal of Urban Health : Bulletin of the New York Academy of Medicine·Prerna Bhasin, Satwanti Kapoor
Jan 30, 2014·Journal of General Internal Medicine·Wendy L BennettJeanne M Clark
Nov 12, 2013·International Journal of Obstetric Anesthesia·A Palanisamy
Sep 27, 2013·Hypertension Research : Official Journal of the Japanese Society of Hypertension·Toshitaka MoriAkihiko Wakatsuki
Aug 21, 2013·European Journal of Endocrinology·H IjäsM Vääräsmäki
Aug 8, 2014·Obstetrical & Gynecological Survey·Galit Levi DunietzLouise Margaret O'Brien
May 20, 2014·Seminars in Perinatology·Tracy AdamsWendy L Kinzler
Jun 28, 2014·The Canadian Journal of Cardiology·Jessica GorguiStella S Daskalopoulou
Dec 3, 2014·Journal of the American Society of Hypertension : JASH·Roberto F MesquitaWilson Nadruz
Dec 3, 2014·Annals of Epidemiology·Wei PerngEmily Oken
May 22, 2013·International Journal of Pediatrics·Julie HakimAntoine M Hakim
May 16, 2012·Journal of Women's Health·Elena V Kuklina, Alexander Shilkrut
Sep 17, 2013·Journal of Women's Health·Janet M CatovRoberta B Ness
Aug 10, 2013·Current Opinion in Cardiology·Deborah B Ehrenthal, Janet M Catov
Aug 6, 2013·Current Cardiovascular Risk Reports·Suttira Intapad, Barbara T Alexander
Apr 8, 2015·The Journal of Maternal-fetal & Neonatal Medicine : the Official Journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians·Talya WolakEyal Sheiner
Aug 15, 2014·Hypertension in Pregnancy : Official Journal of the International Society for the Study of Hypertension in Pregnancy·Helen L BarrettLeonie K Callaway
Dec 19, 2012·Expert Review of Cardiovascular Therapy·Nanette K Wenger
Apr 29, 2014·Expert Opinion on Biological Therapy·Annalisa InversettiSilvia Galbiati
Jan 31, 2016·American Journal of Epidemiology·David M HaasUNKNOWN National Heart, Lung, and Blood Institute nuMoM2b Heart Health Study Network
Nov 6, 2013·The American Journal of Cardiology·Nanette K Wenger
Jan 19, 2016·Journal of Women's Health·Davaasambuu EnkhmaaChrisandra Shufelt
Jan 16, 2016·Journal of Women's Health·Nanette K Wenger
Oct 11, 2012·Current Problems in Cardiology·Eveline Oestreicher Stock, Rita Redberg
Dec 22, 2015·Social Science & Medicine·Bridget J GoosbyThomas McDade
Mar 11, 2015·Acta Obstetricia Et Gynecologica Scandinavica·Lene G RasmussenAnne C Staff
Oct 17, 2015·MCN. the American Journal of Maternal Child Nursing·Adriane Burgess, Sandra Founds
May 4, 2013·BJOG : an International Journal of Obstetrics and Gynaecology·J T DrostW M M Verschuren
Jul 30, 2014·Journal of Midwifery & Women's Health·Dorothy Brewin, Angela Nannini
May 7, 2014·Diabetic Medicine : a Journal of the British Diabetic Association·R A MaitlandUNKNOWN UPBEAT trial consortium
Mar 10, 2016·Obstetrics and Gynecology·Madeline Murguia RiceUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units Networ

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.

Cardiovascular Disease Pathophysiology

Cardiovascular disease involves several different processes that contribute to the pathological mechanism, including hyperglycemia, inflammation, atherosclerosis, hypertension and more. Vasculature stability plays a critical role in the development of the disease. Discover the latest research on cardiovascular disease pathophysiology here.