Associations of sex hormone concentrations with health and life satisfaction in elderly men.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
Seija I EskelinenKerttu M Irjala

Abstract

To analyze associations between sex hormone concentrations and self-rated health and life satisfaction, neuropsychiatric symptoms, or diagnosed depression or dementia in elderly men. The study subjects were men from the community-based Lieto Study (N = 517). Subjects were excluded from the study if they were taking exogenous sex hormones or medication for prostate cancer or for benign prostatic hyperplasia or if data for calculating body mass index (BMI) were missing. Thus, 466 men (64 to 97 years old; mean age, 72 years; mean BMI, 26.9 kg/m(2)) remained for further analysis. After adjustment for age, higher levels of testosterone and free testosterone were associated with better self-rated health. After adjustment for age and BMI, no statistically significant associations were found between sex hormone levels and self-rated health or life satisfaction or most neuropsychiatric symptoms in elderly men. Diagnosed depression was associated with a lower serum testosterone concentration. Higher levels of luteinizing hormone and follicle-stimulating hormone were associated with diagnosed dementia. In this population-based study with high attendance rate, low serum testosterone concentration was associated with diagnosed depression. S...Continue Reading

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Citations

Jul 16, 2010·The Journal of Sexual Medicine·Stacy ElliottUNKNOWN ADT Survivorship Working Group
Jul 20, 2010·Gender Medicine·Anna Nixon AndréassonMats Lekander
Jun 4, 2014·Geriatrics & Gerontology International·Marika SalminenKerttu Irjala
Jan 22, 2019·Nihon Hinyōkika Gakkai zasshi. The japanese journal of urology·Akio TakayanagiNaoya Masumori
Jan 1, 2016·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Guneet Kaur JasujaShalender Bhasin

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