Associations of symptoms, neurocognition, and metacognition with insight in schizophrenia spectrum disorders

Comprehensive Psychiatry
Kevin K S Chan

Abstract

Many persons with schizophrenia experience poor insight and, as a result, are at risk for treatment non-adherence and numerous negative outcomes. However, to date, the etiology of poor insight has not yet been fully elucidated. One recent theory concerning the roots of poor insight in schizophrenia has proposed that it may result, in part, from impairments in metacognition, or the capacity to think about thinking. The present study thus aims to examine whether metacognition is associated with insight even after controlling for the effects of psychiatric symptomatology and neurocognition. In this study, 95 adults with a schizophrenia spectrum disorder were assessed on measures of insight (i.e., awareness of symptoms, treatment needs, and illness consequences), psychiatric symptoms (i.e., positive symptoms, negative symptoms, and general psychopathology), neurocognitive functions (i.e., executive function, memory, and attention), and metacognitive capacities (i.e., self-reflectivity and theory of mind). Univariate correlations followed by stepwise multiple regressions, which controlled for symptoms and neurocognition, indicated that both self-reflectivity and theory of mind were significantly linked with awareness of symptoms; th...Continue Reading

References

Dec 1, 1976·Archives of General Psychiatry·T Van PuttenC Yale
Jan 1, 1987·Schizophrenia Bulletin·S R KayL A Opler
Feb 1, 1995·The Journal of Nervous and Mental Disease·P Lysaker, M Bell
Oct 1, 1994·Archives of General Psychiatry·X F AmadorJ M Gorman
Jun 1, 1993·The American Journal of Psychiatry·X F AmadorJ M Gorman
Nov 28, 1997·Schizophrenia Research·A A CollinsK Birkett
Nov 6, 1998·Journal of Cognitive Neuroscience·V E StoneR T Knight
Mar 30, 2002·The Journal of Nervous and Mental Disease·Paul H LysakerMorris D Bell
Mar 22, 2003·Schizophrenia Research·Alisa R MintzDavid M Romney
Apr 22, 2004·Schizophrenia Research·Aaron T BeckDebbie M Warman
Aug 27, 2004·Schizophrenia Research·Matcheri S KeshavanNina Schooler
May 13, 2005·Schizophrenia Bulletin·Martin Brüne
Feb 3, 2006·Psychiatric Services : a Journal of the American Psychiatric Association·Mark OlfsonJoyce C West
Feb 8, 2007·CNS Drugs·Peter F BuckleyWilliam C Wirshing
Dec 8, 2007·Comprehensive Psychiatry·Katerine OsatukeSomaia Mohamed
May 15, 2008·The Journal of Nervous and Mental Disease·Paul H LysakerGiuseppe Nicolò
May 23, 2008·Schizophrenia Bulletin·Robyn Langdon, Philip Ward
Dec 17, 2008·European Psychiatry : the Journal of the Association of European Psychiatrists·Viktoria SimonRuud van Winkel
Feb 10, 2009·European Psychiatry : the Journal of the Association of European Psychiatrists·Andreas WittorfStefan Klingberg
Jun 16, 2009·The Psychiatric Quarterly·Evgenia StefanopoulouAdam Huxley
Jun 23, 2009·European Psychiatry : the Journal of the Association of European Psychiatrists·M A F De HertR van Winkel
Jul 11, 2009·Expert Review of Neurotherapeutics·Paul H LysakerGiancarlo Dimaggio
Apr 13, 2010·Schizophrenia Research·Benjamin D R WiffenAnthony S David
Jul 9, 2010·The Journal of Nervous and Mental Disease·Cheryl Greenberger, Mark R Serper
Aug 5, 2010·Current Opinion in Psychiatry·Steffen MoritzTodd S Woodward
May 13, 2011·Cognitive Neuropsychiatry·Kevin K S Chan, Eric Y H Chen
Jan 17, 2012·Schizophrenia Research·Sherry K W ChanEric Y H Chen
Jan 22, 2013·Comprehensive Psychiatry·Cinzia MingroneFilippo Bogetto
Dec 11, 2013·Schizophrenia Research·George KonstantakopoulosAnthony S David
Sep 4, 2014·The International Journal of Social Psychiatry·Almila ErolLevent Mete
Apr 23, 2015·The Journal of Nervous and Mental Disease·Jenifer L VohsAlan Breier

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Citations

Jan 21, 2018·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·Paul H LysakerJenifer L Vohs

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