Associations of the ages at menarche and menopause with blood pressure and hypertension among middle-aged and older Chinese women: a cross-sectional analysis of the baseline data of the China Health and Retirement Longitudinal Study

Hypertension Research : Official Journal of the Japanese Society of Hypertension
Luqi ShenChangwei Li

Abstract

We evaluated the associations of the ages at menarche and menopause with blood pressure (BP) and hypertension using the baseline data of 7893 women from the China Health and Retirement Longitudinal Study, a nationally representative survey among Chinese adults aged ≥45 years. Multivariate linear and logistic regression analyses were performed to evaluate the associations of the ages at menarche and men`opause with BP and hypertension, respectively. Nonlinear associations were evaluated using spline analyses. After controlling for age, education, marital status, living areas, smoking, drinking, and medication use if necessary, an early onset of menarche by 1 year was associated with a 6% (95% confidence interval [CI]: 3-9%) higher odds of hypertension and 0.82 mm Hg (P < 0.001) and 0.41 mm Hg (P < 0.001) higher systolic and diastolic BP, respectively. When further controlling for the body mass index (BMI), blood glucose, and lipids, the associations were still significant. Spline analyses did not support U-shaped relationships between menarche age and hypertension risk (P = 0.35), systolic BP (P = 0.60), or diastolic BP (P = 0.70). When stratified by location of residence, menarche age was only associated with BP and hypertensio...Continue Reading

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Citations

Feb 24, 2019·Research and Theory for Nursing Practice·Ping HeTingting Liu
Nov 30, 2019·International Journal of Hypertension·Wei ZhouXiaoshu Cheng
Apr 5, 2021·Nutrition, Metabolism, and Cardiovascular Diseases : NMCD·Chao WangZuxun Lu
Nov 30, 2021·Women & Health·Fahimeh Ramezani Tehrani, Mina Amiri
Sep 15, 2021·Menopause : the Journal of the North American Menopause Society·Huimin SuLin Xu

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Methods Mentioned

BETA
hormone replacement therapy

Software Mentioned

SAS
CHARLS

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