Associative conditioning with leg cycling and inspiratory resistance enhances the early exercise ventilatory response in humans

European Journal of Applied Physiology
Duncan Turner, Jamie D Stewart

Abstract

Repeated trials of hypercapnic exercise [deltaPET CO2 = 7 (1) mmHg] augment the increase in inspired minute ventilation and tidal volume (V(T)) in the early phase of subsequent trials of unencumbered exercise alone. The increase in V(T) in the first 20 s of exercise was correlated to the increase in V(T) evoked during hypercapnic exercise trials, suggesting that the evoked increase in V(T) during conditioning may be a factor in mediating associative conditioning. To test this hypothesis, inspiratory resistive loading (IRL) was employed to evoke an increase in V(T) [deltaV(T) = 0.4 (0.1) I(BTPS)] during conditioning exercise trials [IRL + EX; deltaP(ET)CO2 = 2 (l) mmHg]. IRL + EX associative conditioning elicited a significant augmentation of the early minute ventilation (+46%) and V(T) (+100%) responses to subsequent unencumbered exercise. The latter was correlated to the evoked increase in V(T) during associative conditioning with IRL + EX. The results support the hypothesis that an evoked increase in V(T) during associative conditioning could be a factor in eliciting long-term modulation of minute ventilation in subsequent unencumbered exercise. The results further indicated that the modulation of ventilation early in exercis...Continue Reading

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Citations

Feb 19, 2010·Medicine and Science in Sports and Exercise·Tony G BabbGordon S Mitchell
Apr 10, 2007·Respiratory Physiology & Neurobiology·Chi-Sang PoonYunguo Yu
Mar 15, 2006·Respiratory Physiology & Neurobiology·Gordon S Mitchell, Tony G Babb
May 28, 2013·Respiratory Physiology & Neurobiology·Tony G Babb
Oct 27, 2017·Advances in Physiology Education·Richard M Bruce

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