Abstract
In singletons, asthma may be associated with shorter height and delayed growth during adolescence. Yet, these studies do not account for heritability of asthma, puberty/menarche, and height. We aimed to study the association between asthma and puberty in boys and menarche in girls, and height, in a cohort of twins and subsequently in same-sex twin pairs discordant for asthma. From a Swedish twin cohort, parent- and self-reported data on asthma, puberty/menarche, and height were collected. Pubertal staging was established via the Petersen index. Logistic and linear regression was used to estimate associations between asthma and puberty/menarche and height, respectively. For within-pair analyses in twins discordant for asthma, conditional logistic and linear regression were used. Data on 2,658 (49.1% boys) twins were included. Among boys, asthma prevalence was 8.2% at 8-9 years and 10.2% at 13-14 years. Corresponding numbers for girls were 4.2% and 4.9%, respectively. In the entire cohort, no statistically significant associations were found between current asthma and puberty/menarche. Boys with asthma were shorter than boys without asthma at 8-9 years (on average, 1.86 [0.17-3.56] cm, p = .03) and at 13-14 years (on average, 2.9...Continue Reading
References
Mar 1, 1977·The Journal of Allergy and Clinical Immunology·R HauspieF Alexander
Sep 1, 1981·Acta paediatrica Scandinavica·A J MartinP D Phelan
Mar 1, 1995·The European Respiratory Journal·M I AsherA W Stewart
Jul 1, 1996·Annals of Human Biology·R G NevilleI K Crombie
Dec 24, 1997·Allergy·P Lichtenstein, M Svartengren
Oct 12, 2000·The New England Journal of Medicine·UNKNOWN Childhood Asthma Management Program Research GroupRobert Zeiger
Aug 14, 2001·Pharmacoepidemiology and Drug Safety·E NorjavaaraB Lindmark
Aug 13, 2003·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Thornas NicolaiErika von Mutius
Oct 29, 2003·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·T MoudiouA Papadimitriou
Jan 13, 2006·Behavior Genetics·Stéphanie M van den BergDorret I Boomsma
Aug 29, 2006·Lancet·M Innes AsherUNKNOWN ISAAC Phase Three Study Group
Jun 2, 2007·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Paul LichtensteinEva Carlström
Mar 26, 2008·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Simon Francis ThomsenVibeke Backer
Mar 26, 2008·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Corrado FagnaniMaria Antonietta Stazi
Jan 27, 2009·The Journal of Pediatrics·Robert C StrunkUNKNOWN Childhood Asthma Management Program (CAMP) Research Group
May 22, 2009·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Oliver Mayo
Sep 30, 2009·Pediatrics·Anne Kristina OrtqvistCatarina Almqvist
Jun 10, 2010·Clinical and Experimental Allergy : Journal of the British Society for Allergy and Clinical Immunology·S F ThomsenV Backer
Sep 15, 2010·International Journal of Public Health·Erica E M Moodie, D A Stephens
Feb 16, 2011·Pakistan Journal of Biological Sciences : PJBS·Zainab A El-SayedNermine H Mahmoud
May 24, 2011·Allergy·N MogensenC Almqvist
Dec 16, 2011·Pediatrics International : Official Journal of the Japan Pediatric Society·Norikazu YoshitakeTatsuya Hobara
Mar 22, 2012·Pediatric Obesity·Y WangW J Rogan
Apr 4, 2012·International Journal of Environmental Research and Public Health·Anna-Kristin BrettschneiderAngelika Schaffrath Rosario
Sep 4, 2012·The New England Journal of Medicine·H William KellyUNKNOWN CAMP Research Group
Feb 23, 2013·The Journal of Clinical Endocrinology and Metabolism·M M G KoenisH E Hulshoff Pol
Feb 27, 2013·Respiratory Physiology & Neurobiology·Wioleta UmławskaDorota Sands
Jun 26, 2013·Annals of Human Biology·Theo GasserRemo Largo
Nov 5, 2013·American Journal of Human Genetics·Gibran HemaniPeter M Visscher
Apr 1, 1988·Journal of Youth and Adolescence·A C PetersenA Boxer
Nov 30, 2013·Otolaryngologic Clinics of North America·Minka L Schofield
Dec 18, 2013·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jennifer Lisa Penner ProtudjerCatarina Almqvist
Feb 6, 2014·The Journal of Allergy and Clinical Immunology·Andrew TaiColin F Robertson
May 23, 2014·PloS One·Stéphane LegleyeNearkasen Chau
Citations
Oct 24, 2015·Tissue Antigens·J ChenM Xue
Jan 28, 2020·Twin Research and Human Genetics : the Official Journal of the International Society for Twin Studies·Jeffrey M CraigDedra Buchwald
Sep 19, 2019·Allergy, Asthma, and Clinical Immunology : Official Journal of the Canadian Society of Allergy and Clinical Immunology·Jennifer Lisa Penner ProtudjerAllan Barry Becker
Nov 20, 2016·Respirology : Official Journal of the Asian Pacific Society of Respirology·Maria MovinUNKNOWN Childhood Asthma Prevention Team
Oct 29, 2020·Endocrine·Yuan YuanWenquan Niu