Asthma Flare-up Diary for Young Children to monitor the severity of exacerbations

The Journal of Allergy and Clinical Immunology
Francine M DucharmeRobert Platt

Abstract

Few instruments exist to ascertain the severity of a preschool-aged child's asthma exacerbations managed at home. We sought to develop and validate a functional status instrument to assess asthma exacerbation severity in preschoolers. The parent-completed Asthma Flare-up Diary for Young Children (ADYC), which was developed systematically, comprises 17 items, each scored from 1 (best) to 7 (worst). The ADYC was completed daily from the onset of an upper respiratory tract infection (URTI) until asthma symptom resolution; the cumulative daily score was reported. The ADYC was examined for key psychometric properties in a randomized placebo-controlled trial of pre-emptive high-dose fluticasone in preschoolers with URTI-induced asthma. In 121 children aged 2.7 ± 1.1 years (59.5% male), the ADYC's internal consistency (Cronbach α = .97), feasibility (97% completion), and test-retest reliability (r = 0.71; 95% CI, 0.59-0.80) were demonstrated. The ADYC was responsive to change between 2 consecutive days (Guyatt statistic = 0.77) with a minimal important difference of 0.22 (0.17-0.27). Of 871 episodes, the cumulative ADYC score was significantly higher during exacerbations than during URTIs (mean difference [MD], 7.6; 95% CI, 6.4-8.9) a...Continue Reading

References

Jan 1, 1987·Journal of Chronic Diseases·G GuyattG Norman
Jan 1, 1985·Journal of Chronic Diseases·B Kirshner, G Guyatt
Feb 1, 1996·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·E F JuniperM Townsend
Mar 1, 1997·Journal of Clinical Epidemiology·E F JuniperD R King
Nov 18, 2000·The Journal of Allergy and Clinical Immunology·N C SantanelloB Knorr
Nov 16, 2004·American Journal of Respiratory and Critical Care Medicine·Hans BisgaardPeter Polos
Dec 13, 2006·Journal of Clinical Epidemiology·Caroline B TerweeHenrica C W de Vet
Dec 16, 2006·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Joseph J ZorcJudy A Shea
Mar 14, 2007·The Journal of Allergy and Clinical Immunology·Andrew H LiuRanjani Manjunath
Nov 20, 2008·Chest·M Diane LougheedNigel A M Paterson
Dec 9, 2008·Pediatric Pulmonology·E G Pérez-YarzaUNKNOWN CAN Investigator Group
Jan 24, 2009·The New England Journal of Medicine·Francine M DucharmeRobert W Platt
Apr 8, 2009·The Journal of Allergy and Clinical Immunology·Kevin R MurphySulabha Ramachandran
Jun 30, 2009·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jane M GarbuttRobert C Strunk
Sep 24, 2009·Allergy·A PapiUNKNOWN BEclomethasone and Salbutamol Treatment (BEST) for Children Study Group
Jan 21, 2010·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Jane GarbuttRobert Strunk
Feb 23, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Michael SeidJames W Varni
Nov 3, 2010·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Timothy H SelfJohn C Winton
Nov 25, 2011·The New England Journal of Medicine·Robert S ZeigerUNKNOWN CARE Network of the National Heart, Lung, and Blood Institute
Nov 13, 2012·The European Respiratory Journal·Amy BarrettDirk Esser
Nov 28, 2012·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Kelly ClaytonKathy Harrington
Feb 26, 2013·The Journal of Allergy and Clinical Immunology·Sande O OkeloKristin A Riekert
Jun 29, 2013·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Margaret L BurksPamela R Wood
Oct 2, 2013·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·S van BragtT Schermer
Nov 13, 2013·Pediatrics·Flory L NkoyChristopher G Maloney
Mar 4, 2014·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·Erdem TopalIpek Turktas
Mar 13, 2014·The Journal of Allergy and Clinical Immunology. in Practice·Sande O OkeloCecilia M Patino

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Citations

Oct 5, 2017·Expert Review of Respiratory Medicine·Antonio José Justicia-GrandeFederico Martinón-Torres
Sep 2, 2019·Archives of Disease in Childhood. Education and Practice Edition·Heidi MakriniotiChris Griffiths
Mar 28, 2019·NPJ Primary Care Respiratory Medicine·Makrinioti HeidiBush Andrew

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