Asthma overview

Primary Care
Ronald Balkissoon

Abstract

This article presents our current understanding of the biological heterogeneity of asthma and reviews some of the key features of the latest proposed recommendations of the National Asthma Education and Prevention Program Guidelines. The diagnosis of asthma is based on such clinical features as variable airflow obstruction that is partially if not fully reversible and airway hyperresponsiveness that predisposes to episodic bronchospasm following exposure to a variety of triggers. The underlying inflammation and airway biology of asthma is heterogeneous and is part of the explanation for the variable response to therapy. New biologics that help to characterize patients according to their underlying biology will aid in making better choices for treatment. New asthma guidelines emphasize the importance of regular monitoring.

References

Dec 22, 1998·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·P E Silkoff, R J Martin
Jan 7, 2000·The American Journal of Medicine·P D Blanc, K Toren
Sep 12, 2000·Clinical Reviews in Allergy & Immunology·P A Eggleston
Jun 13, 2001·American Journal of Respiratory and Critical Care Medicine·M KraftC G Irvin
Sep 1, 2001·The European Respiratory Journal·M SolèrG Della Cioppa
Oct 9, 2001·The Journal of Allergy and Clinical Immunology·P M O'ByrneK Parameswaran
Apr 20, 2002·Current Opinion in Allergy and Clinical Immunology·Amrutha D HollaAndrew H Liu
Jan 10, 2004·The Journal of Allergy and Clinical Immunology·Christina MirandaSally E Wenzel
Apr 24, 2004·The Cochrane Database of Systematic Reviews·B G Toelle, F S F Ram
Sep 10, 2004·American Journal of Respiratory and Critical Care Medicine·Sally E Wenzel
Apr 26, 2005·American Journal of Respiratory and Critical Care Medicine·Sally Wenzel
Dec 3, 2005·American Journal of Respiratory and Critical Care Medicine·Michael E WechslerUNKNOWN National Heart, Lung, and Blood Institute's Asthma Clinical Research Network
Mar 18, 2006·Clinics in Chest Medicine·Sally Wenzel
Mar 18, 2006·Clinics in Chest Medicine·David J Slade, Monica Kraft
May 6, 2006·The Journal of Allergy and Clinical Immunology·Bianca SchaubErika von Mutius
May 10, 2006·Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology·David H Dreyfus, Christopher C Randolph
Jun 6, 2006·The Journal of Allergy and Clinical Immunology·John V Fahy
Jul 19, 2006·Canadian Journal of Physiology and Pharmacology·Catherine Lemiere
Jul 21, 2006·The Cochrane Database of Systematic Reviews·S BhogalF M Ducharme
Aug 29, 2006·Lancet·Sally E Wenzel
Jan 9, 2007·The Journal of Allergy and Clinical Immunology·William W Busse, Herman Mitchell
Jan 16, 2007·Current Opinion in Allergy and Clinical Immunology·Frederick E Hargreave
Feb 1, 2007·Evidence-based Medicine·P John Rees
May 17, 2007·Current Allergy and Asthma Reports·Thomas Hilberg
May 29, 2007·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·Sally WenzelJudith Harris
Jul 11, 2007·Allergy and Asthma Proceedings·Kursteen S Price, Robert G Hamilton

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Citations

Dec 20, 2012·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Laura E Crotty AlexanderVictor Nizet
Jan 1, 2008·The Open Medicinal Chemistry Journal·Rajan Subramanian KombuRaghu Ram Rao Akkinepally
Oct 15, 2014·Journal of Voice : Official Journal of the Voice Foundation·Jackie L Gartner-SchmidtClark A Rosen
May 5, 2009·Chronic Respiratory Disease·A EntezariM Moin
May 18, 2019·Journal of Cellular Physiology·Seyed Reza MousaviJafar Salimian
Nov 26, 2010·The Journal of Immunology : Official Journal of the American Association of Immunologists·Yiming Zhu, Paul J Bertics

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