Asthma treatment during pregnancy. What can be safely taken?

Drug Safety : an International Journal of Medical Toxicology and Drug Experience
M Schatz

Abstract

'Safe' pharmacological therapy for gestational asthma is defined as therapy during which the apparent risks of the drug appear to be lower than the maternal and potential fetal risks of uncontrolled asthma that could result if the drug were not used. Major malformations occur in 2 to 4% of all newborns, 1% of which can be attributed to medication in general. Information regarding the effects of drugs administered during pregnancy may come from animal studies, human case reports, and prospective cohort studies. Based on a review of the available information, it is recommended that mild asthma during pregnancy be managed with inhaled beta 2-agonists, as required; step therapy for moderate asthma would include inhaled sodium cromoglycate (cromolyn sodium), inhaled beclomethasone dipropionate and oral theophylline. Severe gestational asthma should be treated with oral corticosteroids at the lowest effective dosage. The pharmacological management of acute asthma during pregnancy should include nebulised beta 2-agonists and ipratropium bromide, and intravenous methylprednisolone. Intravenous aminophylline would not generally be recommended, unless the patient requires hospitalisation. Optimal medical practice medico-legal considerati...Continue Reading

Citations

May 2, 2002·MCN. the American Journal of Maternal Child Nursing·Claudia Anderson Beckmann
Sep 3, 1999·American Journal of Respiratory and Critical Care Medicine·R K CydulkaC A Camargo
Nov 24, 2007·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Petros V VlastarakosGeorge Kreatsas
Feb 13, 2008·European Archives of Oto-rhino-laryngology : Official Journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : Affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery·Petros V VlastarakosThomas P Nikolopoulos
Jan 31, 2006·Immunology and Allergy Clinics of North America·Rita K Cydulka
Oct 19, 2004·Rheumatic Diseases Clinics of North America·K Arnold Chan, Sonia Hernandez-Diaz
Apr 20, 2010·Respiratory Medicine·Faranak FirooziLucie Blais
Sep 2, 2008·Respiratory Medicine·Faranak FirooziLucie Blais
May 7, 2020·British Journal of Clinical Pharmacology·Eline HoubenRon M C Herings
Mar 2, 2013·Pharmacotherapy·Catherine Vasilakis-ScaramozzaSusan S Jick
May 31, 2021·Revue des maladies respiratoires·T Stoup, C Chenivesse

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