Astragalus injection for hypertensive renal damage: a systematic review.

Evidence-based Complementary and Alternative Medicine : ECAM
Tian SunFengqin Xu

Abstract

Objective. To evaluate the effectiveness of astragalus injection (a traditional Chinese patent medicine) for patients with renal damage induced by hypertension according to the available evidence. Methods. We searched MEDLINE, China National Knowledge Infrastructure (CNKI), Chinese VIP Information, China Biology Medicine (CBM), and Chinese Medical Citation Index (CMCI), and the date of search starts from the first of database to August 2011. No language restriction was applied. We included randomized controlled trials testing astragalus injection against placebo or astragalus injection plus antihypertensive drugs against antihypertensive drugs. Study selection, data extraction, quality assessment, and data analyses were conducted according to the Cochrane review standards. Results. 5 randomized trials (involving 429 patients) were included and the methodological quality was evaluated as generally low. The pooled results showed that astragalus injection was more effective in lowering β(2)-microglobulin (β(2)-MG), microalbuminuria (mAlb) compared with placebo, and it was also superior to prostaglandin in lowering blood urea nitrogen (BUN), creatinine clearance rate (Ccr). There were no adverse effects reported in the trials from ...Continue Reading

References

May 13, 2008·Zhong xi yi jie he xue bao = Journal of Chinese integrative medicine·Gui-Hua XuYong-Hua Chen

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Citations

Jan 23, 2016·Evidence-based Complementary and Alternative Medicine : ECAM·Shumei Mao, Chengde Li
Sep 27, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Changtai ZhuYang Ling
Aug 30, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Jie WangXingjiang Xiong
Jul 24, 2013·Evidence-based Complementary and Alternative Medicine : ECAM·Xingjiang XiongJie Wang
Aug 5, 2016·Expert Review of Proteomics·Tongchuan SuoZheng Li

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