Astrobiological aspects of the mutagenesis of cosmic radiation on bacterial spores

Astrobiology
Ralf MoellerG Horneck

Abstract

Based on their unique resistance to various space parameters, Bacillus endospores are one of the model systems used for astrobiological studies. In this study, spores of B. subtilis were used to study the effects of galactic cosmic radiation (GCR) on spore survival and induced mutagenesis. In interplanetary space, outside Earth's protective magnetic field, spore-containing rocks would be exposed to bombardment by high-energy charged particle radiation from galactic sources and from the Sun, which consists of photons (X-rays, gamma rays), protons, electrons, and heavy, high-energy charged (HZE) particles. B. subtilis spores were irradiated with X-rays and accelerated heavy ions (helium, carbon, silicon and iron) in the linear energy transfer (LET) range of 2-200 keV/mum. Spore survival and the rate of the induced mutations to rifampicin resistance (Rif(R)) depended on the LET of the applied species of ions and radiation, whereas the exposure to high-energy charged particles, for example, iron ions, led to a low level of spore survival and increased frequency of mutation to Rif(R) compared to low-energy charged particles and X-rays. Twenty-one Rif(R) mutant spores were isolated from X-ray and heavy ion-irradiated samples. Nucleot...Continue Reading

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Citations

Aug 11, 2018·Astrobiology·Dimitri VerasHendrik Schäefer
Jan 1, 2014·Applied and Environmental Microbiology·Yun XingLarry W Burggraf
Apr 23, 2020·Frontiers in Microbiology·Marta CortesãoRalf Moeller
Sep 29, 2020·Frontiers in Microbiology·Yuko KawaguchiAkihiko Yamagishi
Sep 9, 2021·Applied and Environmental Microbiology·Joss D Leehan, Wayne L Nicholson

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Methods Mentioned

BETA
X-ray
PCR

Software Mentioned

CLUSTALW
DNAsis
MedProbe

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