Asymmetric Copper-Catalyzed Carbomagnesiation of Cyclopropenes

Angewandte Chemie
Longyang DianIlan Marek

Abstract

The highly diastereo- and enantioselective formation of polysubstituted cyclopropanes was easily achieved through the asymmetric copper-catalyzed carbomagnesiation reaction of nonfunctionalized cyclopropene derivatives. The carbometalated species generated in situ readily undergo C-C and C-X bond-forming reactions with various electrophiles with complete retention of configuration.

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Citations

Sep 19, 2017·Organic & Biomolecular Chemistry·Pavel YamanushkinMichael Rubin
Apr 26, 2018·Chemistry : a European Journal·Ilan MarekMarwan Simaan
Aug 26, 2018·Angewandte Chemie·Jacob Werth, Christopher Uyeda
May 4, 2018·Angewandte Chemie·Andreu TortajadaRuben Martin
Jan 25, 2019·Angewandte Chemie·Marc Montesinos-MagranerAbraham Mendoza
Sep 19, 2019·Chemistry : a European Journal·Liangliang Zhang, Martin Oestreich
Apr 18, 2019·Beilstein Journal of Organic Chemistry·Marwan Simaan, Ilan Marek
May 15, 2020·Chemical Communications : Chem Comm·Penghua LiMin Shi
Apr 25, 2019·Chemical Science·Yang Yang, Ji-Woong Lee
Dec 16, 2017·Organic & Biomolecular Chemistry·Vladimir MaslivetcMichael Rubin
Apr 2, 2021·Angewandte Chemie·Xiao-Wang ChenDa-Gang Yu
Jun 8, 2021·Chemical Science·Veeranjaneyulu Lanke, Ilan Marek
Mar 15, 2018·The Journal of Organic Chemistry·Jeffrey BruffaertsIlan Marek
Sep 22, 2020·ACS Catalysis·Longyang Dian, Ilan Marek
Mar 1, 2019·ACS Catalysis·Heiko SommerIlan Marek
Nov 10, 2017·Journal of the American Chemical Society·Huai-Long TengZhaomin Hou
Nov 11, 2017·Journal of the American Chemical Society·Yong-Yuan GuiDa-Gang Yu
Mar 7, 2020·Journal of the American Chemical Society·Veeranjaneyulu Lanke, Ilan Marek

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