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Asymmetric TDP-43 distribution in primary progressive aphasia with progranulin mutation

Neurology

May 19, 2010

G GliebusChangiz Geula

Abstract

Primary progressive aphasia (PPA) results from an asymmetric degeneration of the language dominant (usually left) hemisphere and can be associated with the pathology of Alzheimer disease (AD) or frontotemporal lobar degeneration (FTLD). This study aimed to investigate whether the anatom...read more

Mentioned in this Paper

TARDBP gene
GRN gene
Abnormal Degeneration
Primary Progressive Aphasia (Disorder)
Neurofibrillary Degeneration (Morphologic Abnormality)
Entire Inferior Temporal Gyrus
Neurons
TARDBP
Brain
GRN
Paper Details
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Asymmetric TDP-43 distribution in primary progressive aphasia with progranulin mutation

Neurology

May 19, 2010

G GliebusChangiz Geula

PMID: 20479359

DOI: 10.1212/wnl.0b013e3181df0a1b

Abstract

Primary progressive aphasia (PPA) results from an asymmetric degeneration of the language dominant (usually left) hemisphere and can be associated with the pathology of Alzheimer disease (AD) or frontotemporal lobar degeneration (FTLD). This study aimed to investigate whether the anatom...read more

Mentioned in this Paper

TARDBP gene
GRN gene
Abnormal Degeneration
Primary Progressive Aphasia (Disorder)
Neurofibrillary Degeneration (Morphologic Abnormality)
Entire Inferior Temporal Gyrus
Neurons
TARDBP
Brain
GRN

Similar Papers Found In These Feeds

ALS: Genetics

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder characterized by muscle weakness. ALS is a genetically heterogeneous disorder with several causative genes. Here are the latest discoveries pertaining to the genetics of this disease.

Frontotemporal Lobar Degeneration

Frontotemporal lobar degeneration or frontotemporal dementia refers to a group of uncommon disorders that occur as a result of progressive nerve cell loss in the frontal and temporal lobes of the brain. Here is the latest research.

Related Papers

Current Opinion in Neurology

The logopenic variant of primary progressive aphasia

Current Opinion in NeurologySeptember 21, 2010
Maya L Henry, Maria Luisa Gorno-Tempini
Paper Details
References
  • References
  • Citations15
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
  • References
  • Citations15
12
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