Asymmetry in the occlusal morphology of first permanent molars in 45,X/46,XX mosaics

Archives of Oral Biology
P PirttiniemiP Karjalahti

Abstract

The genetic control of dental morphology is affected by various chromosomal aberrations, and morphological changes familiar to specific aneuploidies can be distinguished in many cases. Asymmetry between bilateral teeth in the dental arch in laboratory animals shows increased expression after exposure to external stress during development. Bilateral asymmetry in occlusal cuspal morphology has not been widely used as a means of odontometric examination, partly because accurate and reliable methods are not commonly available. The aim here was to examine linear and angular variables of the occlusal morphology of maxillary and mandibular first permanent molars in three dimensions in individuals with 45,X/46,XX mosaicism and to find out if this aneuploidism causes deviations from normal development and increased asymmetry in bilateral variables of the occlusal surface. The participants were five females with 45,X/46,XX chromosome constitution, whose karyotypes were confirmed by cytogenetic tests of skin fibroblasts. The controls were 10 first-degree female relatives of the mosaic patients with normal 46,XX chromosome constitution. The method of measuring the three-dimensional morphology of occlusal surfaces was based on a machine-vis...Continue Reading

References

Jan 1, 1977·American Journal of Physical Anthropology·W J Doyle, O Johnston
Jan 1, 1977·American Journal of Physical Anthropology·M I SiegelC Kelley
Jan 1, 1975·American Journal of Physical Anthropology·R H Biggerstaff
Jan 1, 1991·Archives of Oral Biology·J T MayhallG C Townsend
Jan 1, 1989·American Journal of Physical Anthropology·J T Mayhall, E Kanazawa
Jan 1, 1988·Archives of Oral Biology·J VarrelaL Alvesalo
Dec 1, 1987·Human Genetics·L AlvesaloE Therman
Mar 1, 1986·American Journal of Physical Anthropology·J T Mayhall, S R Saunders
Aug 1, 1985·Australian Dental Journal·G Townsend, L Alvesalo
Sep 1, 1969·Journal of Medical Genetics·I H PorterB A Paul
Feb 1, 1980·American Journal of Physical Anthropology·H S Barden
Dec 1, 1984·American Journal of Physical Anthropology·G TownsendL Alvesalo
Jan 1, 1982·Archives of Oral Biology·S R Saunders, J T Mayhall
Jul 1, 1982·American Journal of Physical Anthropology·B H SmithP E Cole
May 1, 1981·American Journal of Physical Anthropology·R S Corruccini, R H Potter
Sep 1, 1994·Journal of Medical Genetics·C G WoodsD Wellesley

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Citations

Oct 12, 1999·American Journal of Physical Anthropology·A M Albert, D L Greene
Apr 25, 2012·Odontology·Roshan PeirisEisaku Kanazawa
Feb 11, 2000·Archives of Oral Biology·M GrönL Alvesalo
Jun 3, 2014·Acta Odontologica Scandinavica·Raija Helena PentinpuroLassi Juhani Alvesalo
Jan 27, 2004·Journal of Dental Research·R KanomiK Takada
Dec 25, 2008·Homo : internationale Zeitschrift für die vergleichende Forschung am Menschen·G A BolliniS E Colantonio
Nov 16, 2018·PloS One·Mitsuko NakayamaRaija Lähdesmäki

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