Asymmetry of the frontal aslant tract is associated with lexical decision

Brain Structure & Function
Antonino Vallesi, Laura Babcock

Abstract

The frontal aslant tract (FAT) is a recently documented white matter tract that connects the inferior and superior frontal gyri with a tendency to be more pronounced in the left hemisphere. This tract has been found to play a role in language functions, particularly verbal fluency. However, it is not entirely clear to what extent FAT asymmetry is related to performance benefits in language-related tasks. In the present study, we aimed to fill this gap by examining the correlations between asymmetric micro- and macro-structural properties of the FAT and performance on verbal fluency and lexical decision tasks. The results showed no correlation between the FAT and verbal fluency; however, lexical decision was correlated with FAT laterality. Specifically, greater left lateralization in both micro- and macro-structural properties was related to faster lexical decision response times. The results were not due merely to motor or decision-making processes, as responses in a simple discrimination control task showed no correlation with laterality. These data are the first to suggest a role for the FAT in mediating processes underlying lexical decision.

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Citations

Mar 19, 2021·Frontiers in Neurology·Emanuele La CorteGraziano Serrao

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Methods Mentioned

BETA
SMAs
dissections
dissection

Software Mentioned

ExploreDTI
Natbrainlab
SPSS Statistics

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