Nov 22, 2002

Asymmetry of the parental craniofacial skeleton in orofacial clefting

Journal of Orthodontics
G T McIntyre, Peter A Mossey


To evaluate size-related and shape-related craniofacial skeletal asymmetries in the parents of children with orofacial clefting (OFC). Retrospective PA cephalometric study. Glasgow/Dundee, Scotland. Ninety-two parental volunteers from a completely ascertained sample of 286 children born with OFC between 1980-1984 in the West of Scotland. None. A conventional cephalometric asymmetry analysis (CCAA) evaluated size-related right:left asymmetry comprising eight linear distance, nine angular, and three mid-facial area measurements. The right and left landmark configurations were uniformly scaled using Procrustes superimposition and Euclidean Distance Matrix Analysis (EDMA) evaluated shape-related right-left asymmetry. The three linear distances, nine angles and two areas differed between the right and left sides of the craniofacial complex (P <0.05) indicate size asymmetry characterized by a wider left side of the face and a shorter vertical dimension on the right side (directional asymmetry). EDMA detected shape asymmetry [T statistic = 2.671 (P = 0.10)]. Forty per cent of the EDMA ratios were clinically importantly larger or smaller on the left and right sides respectively, involving landmarks anatomically and morphogenetically im...Continue Reading

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Mentioned in this Paper

Family Health Status
Cleft Palate, Isolated
Skeletal System
Cleft Lip
Orofacial Cleft 1
Retrospective Studies
Entire Skeleton

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