Asymptomatic Leishmania infantum infection in an area of northwestern Italy (Piedmont region) where such infections are traditionally nonendemic.

Journal of Clinical Microbiology
Alberto BiglinoEzio Ferroglio

Abstract

The prevalence of Leishmania infantum-specific antibodies and asymptomatic infection was assessed in a randomized sample of 526 healthy adults from a continental area of northwestern Italy where L. infantum is not endemic and where autochthonous cases of visceral leishmaniasis (VL) were recently reported. L. infantum-specific antibodies were detected by Western blotting (WB) in 39 subjects (7.41%), while L. infantum kinetoplast DNA was amplified from buffy coat in 21 out of 39 WB-positive subjects, confirming asymptomatic infection in 53.8% of seropositives. Risk factors significantly associated with WB positivity were uninterrupted residence since childhood in a local rural environment (odds ratio [OR], 3.5; 95% confidence interval [CI], 1.7 to 7.3), daily contact with animals though not exclusively with dogs (OR, 3.7; 95% CI, 1.3 to 10.7), older age (OR, 2.31; 95% CI, 1.2 to 4.5), and agricultural/other outdoor activities (OR, 3.8; 95% CI, 0.99 to 3.7.) Logistic regression analysis showed that uninterrupted residence in a local rural environment and an age of >65 years were the only independent predictors of seropositivity assessed by WB. Follow-up at 24 months did not show evidence of VL in either seropositive or PCR-positiv...Continue Reading

References

Jan 1, 1985·Annales De Parasitologie Humaine Et Comparée·E PozioM Gramiccia
Nov 1, 1995·Transactions of the Royal Society of Tropical Medicine and Hygiene·P MartyJ Kubar
Apr 1, 1997·Clinical Microbiology Reviews·J AlvarJ Moreno
Jul 1, 1997·The American Journal of Tropical Medicine and Hygiene·A CascioL Titone
Aug 1, 1997·The American Journal of Tropical Medicine and Hygiene·K G LuzC B Palatnik-de Sousa
May 24, 2001·Transactions of the Royal Society of Tropical Medicine and Hygiene·E E Zijlstra, A M el-Hassan
Jan 5, 2002·Journal of Clinical Microbiology·Laurence LachaudPatrick Bastien
Dec 18, 2003·Annals of Tropical Medicine and Parasitology·M DeniauP Marty
Jan 8, 2004·Canadian Journal of Anaesthesia = Journal Canadien D'anesthésie·Nermin HalkicFrançois Mosimann
Aug 3, 2004·Transfusion Medicine·P Mathur, J C Samantaray
Nov 6, 2004·Journal of Clinical Microbiology·Charles MaryHenri Dumon
Jul 6, 2005·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·T WeitzelUNKNOWN Surveillance Importierter Infektionen in Deutschland (SIMPID) Surveillance Network
Jul 28, 2005·Microbes and Infection·Didier BassetJean-Pierre Dedet
Sep 16, 2005·International Journal for Parasitology·Marina Gramiccia, Luigi Gradoni
Oct 8, 2005·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Claudia ColombaLucina Titone
Dec 2, 2005·Emerging Infectious Diseases·Ezio FerroglioLucca Rossi
Dec 14, 2005·Transactions of the Royal Society of Tropical Medicine and Hygiene·E FerroglioA Biglino
Sep 13, 2006·Transfusion·Lisa J Cardo
Oct 20, 2006·Journal of Clinical Microbiology·José A García-GarcíaJuan A Pineda
Sep 20, 2007·Annals of Tropical Medicine and Parasitology·P MartyY Le Fichoux
Dec 7, 2007·Lancet·G RezzaUNKNOWN CHIKV study group
Feb 23, 2008·The Lancet Infectious Diseases·Spinello AntinoriMario Corbellino
Mar 7, 2008·Transactions of the Royal Society of Tropical Medicine and Hygiene·Francesco ScarlataLucina Titone
Apr 11, 2008·Clinical Microbiology Reviews·Jorge AlvarJavier Moreno
Nov 26, 2008·Liver Transplantation : Official Publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society·Isabel Campos-VarelaRamón Charco

❮ Previous
Next ❯

Citations

Sep 14, 2011·Journal of Tropical Medicine·Krystal J Evans, Lukasz Kedzierski
Dec 29, 2012·PLoS Neglected Tropical Diseases·Letícia Helena dos Santos MarquesMariângela Carneiro
Mar 6, 2013·PLoS Neglected Tropical Diseases·Epco HaskerShyam Sundar
Aug 10, 2013·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·S VaraniM P Landini
Aug 10, 2013·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·K Šiško-KraljevićV Punda-Polić
Aug 10, 2013·Euro Surveillance : Bulletin Européen Sur Les Maladies Transmissibles = European Communicable Disease Bulletin·C ChicharroI Cruz
Jun 19, 2012·Future Microbiology·Sezen Canim AtesOlga Nehir Oztel
Mar 13, 2014·International Journal of Environmental Research and Public Health·Adriana CalderaroFlora De Conto
Mar 1, 2014·Vector Borne and Zoonotic Diseases·Annalisa SantiMarco Tamba
Dec 3, 2014·Travel Medicine and Infectious Disease·Pasquale MansuetoAntonio Cascio
May 3, 2011·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·S AntinoriM Corbellino
Sep 4, 2013·Journal of Infection and Public Health·Giuma Harun AbdalmaulaEmilia Prospero
May 30, 2015·Veterinary Parasitology·Carla Maia, Luís Cardoso
Oct 30, 2014·Journal of the European Academy of Dermatology and Venereology : JEADV·M N JabbourI Khalifeh
Oct 11, 2013·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·B FaucherR Piarroux
Nov 4, 2011·Human Vaccines·Lukasz Kedzierski
Jan 7, 2014·Travel Medicine and Infectious Disease·Urs EhehaltJakob P Cramer
Aug 22, 2013·Transfusion and Apheresis Science : Official Journal of the World Apheresis Association : Official Journal of the European Society for Haemapheresis·Adriana de Oliveira FrançaMaria Elizabeth Cavalheiros Dorval
May 21, 2016·Transactions of the Royal Society of Tropical Medicine and Hygiene·Sultana S BanuRogan Lee
Dec 17, 2014·PLoS Neglected Tropical Diseases·Medhavi SudarshanShyam Sundar
Jan 13, 2015·Veterinary Parasitology·Maria Grazia Pennisi
Mar 17, 2017·Vector Borne and Zoonotic Diseases·Gianluca RugnaGiuseppe Merialdi
Oct 5, 2018·Journal of Wildlife Diseases·Lisa YonDolores Gavier-Widén
Apr 16, 2020·Parasites & Vectors·Jairo Mendoza-RoldanDomenico Otranto
Aug 14, 2020·PLoS Neglected Tropical Diseases·Om Prakash SinghShyam Sundar
Jun 21, 2018·Molecular Diagnosis & Therapy·Shyam Sundar, Om Prakash Singh
Nov 30, 2018·International Journal of Environmental Research and Public Health·Giorgia TasciniSusanna Esposito
Mar 27, 2020·PLoS Neglected Tropical Diseases·Maude F LévêqueLaurence Lachaud
Mar 12, 2020·Frontiers in Cellular and Infection Microbiology·Maude F LévêqueChristelle Pomares

❮ Previous
Next ❯

Related Concepts