Asymptomatic lumbosacral lipomas--a natural history study.

Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery
Victoria WykesDominic N P Thompson

Abstract

Inevitable deterioration due to mechanical tethering is perceived as the natural history for complex congenital spinal lipomas of the conus medullaris region, even if asymptomatic at presentation. The conventional wisdom that prophylactic surgical untethering improves outcome has been challenged recently [1, 2]. This study examines the natural history of asymptomatic un-operated children with lumbosacral lipomas (LSL) and investigates whether predictive factors herald deterioration. Over the past decade, children presenting with complex LSL to a single clinician at Great Ormond Street Hospital (GOSH), London, UK have undergone a thorough assessment focusing on neurological and urological evaluation and MRI of the lumbosacral spine. For children deemed to be asymptomatic, conservative management has been adopted with close periodic surveillance of neurological and urological function, thus avoiding untethering surgery unless symptomatic deterioration occurs. A retrospective review identified this cohort of children asymptomatic of their LSL and their progress closely recorded. This study suggests that the natural history of this subgroup of dysraphic patients may be more benign than hitherto considered. Conservative management w...Continue Reading

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Citations

Mar 21, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Lindy MayDominic Thompson
Sep 10, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Laura Grazia ValentiniMarika Furlanetto
Sep 10, 2013·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dachling PangGreg S Moes
Apr 1, 2014·Journal of Neurosurgery. Pediatrics·Jetan H BadhiwalaAbhaya V Kulkarni
Aug 8, 2015·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dylan J GoodrichW Jerry Oakes
Jan 13, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Albert TuD Douglas Cochrane
Sep 9, 2015·Neurologia Medico-chirurgica·Dachling Pang
Apr 16, 2016·Journal of Neurosurgery. Pediatrics·Albert TuD Douglas Cochrane
Apr 18, 2015·Journal of Neurosurgery. Pediatrics·Assem M Abdel Latif, Mark M Souweidane
Nov 15, 2014·Journal of Neurosurgery. Pediatrics·Sara HanaeiMostafa El Khashab
Nov 1, 2016·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sandra Pérez da RosaMaurice Choux
May 26, 2017·Surgical Neurology International·Kathryn M WagnerSandi Lam
Mar 30, 2018·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Victoria Jones, Dominic Thompson
Oct 30, 2016·Asian Spine Journal·Toshitaka SekiKiyohiro Houkin
Jun 4, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sangjoon ChongKyu-Chang Wang
Sep 11, 2019·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Hugo Layard HorsfallDominic Thompson
Feb 27, 2017·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Thomas RoujeauMichel Zerah
Aug 10, 2019·BMC Neurology·Luca MassimiMassimo Caldarelli
Jun 9, 2018·Asian Spine Journal·Toshitaka SekiKiyohiro Houkin
May 10, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Branavan ManoranjanOlufemi Ajani
Jul 31, 2020·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Laura Grazia ValentiniGiorgio Selvaggio
May 13, 2020·Journal of Korean Neurosurgical Society·Dachling Pang
Jan 7, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Tarang K VoraVedantam Rajshekhar
Feb 20, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Dominic N P ThompsonDivyesh Desai
Nov 4, 2021·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Sauradeep SarkarVedantam Rajshekhar

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