Asynchronously Calibrated Quantitative Bone Densitometry

Journal of Clinical Densitometry : the Official Journal of the International Society for Clinical Densitometry
J Keenam BrownR DeJournett

Abstract

Conventional quantitative computed tomography (QCT) uses a phantom scanned simultaneously with the anatomical region of interest. A newly developed method called asynchronous QCT does not require a phantom to be present during the patient scan. This allows the inclusion of computer tomography scans performed without any calibration standard in a different clinical context than bone densitometry, for example, in a screening context. In the present study, the asynchronous and the conventional quantitative computed tomographies were compared. Specifically, short-term precision, a phantom-induced bias, methodical equivalence of the asynchronous and the conventional methods, and interobserver variability were investigated. Ten phantom scans served for investigation of short-term precision. A prospective dataset of 43 study participants (44-80 years, mean 63.8 ± 8.6 years) was acquired over 3 clinical sites. Trabecular regions of the spine as well as cortical and trabecular regions of the hip (femoral neck, trochanter, intertrochanter, and shaft) were analyzed with respect to the presence or absence of a phantom and with regard to the synchronous and asynchronous calibration methods. Regarding precision, all variations of the mean ar...Continue Reading

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Citations

Oct 21, 2016·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Timothy J ZiemlewiczPerry J Pickhardt
Mar 4, 2017·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Johannes KaesmacherYu-Mi Ryang
Apr 18, 2018·Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research·Annette L AdamsTony M Keaveny
May 31, 2018·Current Osteoporosis Reports·Fjola JohannesdottirMary L Bouxsein
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Jun 15, 2019·Radiographics : a Review Publication of the Radiological Society of North America, Inc·Fernando U KayPrabhakar Rajiah
Nov 16, 2019·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M T LöfflerT Baum
Mar 5, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ichiro OkanoAlexander P Hughes
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Mar 15, 2020·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·I OkanoA P Hughes
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Oct 12, 2020·European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society·Ichiro OkanoAlexander P Hughes
Feb 16, 2020·Medical Engineering & Physics·Andrew S MichalskiSteven K Boyd
Nov 8, 2019·World Neurosurgery·Colleen RentenbergerAlexander P Hughes
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Dec 5, 2021·Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society·Manuel MoserAlexander P Hughes

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